Protein Alignment Wwox and Cbr1

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_031646.2
• Gene: Cbr1 / 12408
• MGIID: 88284
• Length: 277
• Species: Mus musculus
• Alignment Length: 277
• Identity: 62/277 - (22%)
• Similarity: 116/277 - (41%)
• Gaps: 71/277 - (25%)

  Fly   124 ALITGANCGIGYETARSLAH-HGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSLR 187
            ||:||||.|||:...|.|.. ...:::.|.|:....:.|::::..|..:.    ||..||:.:.:
Mouse     8 ALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSP----RFHQLDIDNPQ 68

  Fly   188 SVQRFVEEIKQSVSHIDYLILNAGV-FALPYTRTVDGLETTF----QVSHLSHFYLT----LQLE 243
            |::...:.:.:....:|.|:.|||: |.:       ..:|.|    :|:..::|:.|    .:|.
Mouse    69 SIRALRDFLLKEYGGLDVLVNNAGIAFKV-------NDDTPFHIQAEVTMKTNFFGTRDVCKELL 126

  Fly   244 TLFDYKTRIIVLSS---------------ESHRFANLPVENL-------------AVHHLSPPPE 280
            .|...:.|::.:||               :..|...:..|.|             .||     .|
Mouse   127 PLIKPQGRVVNVSSMVSLRALKNCRLELQQKFRSETITEEELVGLMNKFVEDTKKGVH-----AE 186

  Fly   281 KYWSMMAYNNAKLCNVLFAQELAQRW--KQRG--ISVFSLHPGNMVSSDLSRNYWFYRLLFAIVR 341
            :.|...||...|:...:.::.||::.  ::||  |.:.:..|| .|.:|::.            .
Mouse   187 EGWPNSAYGVTKIGVTVLSRILARKLNEQRRGDKILLNACCPG-WVRTDMAG------------P 238

  Fly   342 PFTKSLQQAAATSIYCA 358
            ..|||.::.|.|.:|.|
Mouse   239 KATKSPEEGAETPVYLA 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	62/277 (22%)
Cbr1	NP_031646.2	carb_red_PTCR-like_SDR_c	7..277	CDD:187585	62/277 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..277