Protein Alignment Wwox and LOC100497142

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: XP_002932135.3
• Gene: LOC100497142 / 100497142
• XenbaseID: XB-GENE-29083527
• Length: 352
• Species: Xenopus tropicalis
• Alignment Length: 290
• Identity: 88/290 - (30%)
• Similarity: 158/290 - (54%)
• Gaps: 14/290 - (4%)

  Fly   114 LHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRF 178
            |..|.|.|:|.||||...|||.|||.:||..|..:|....:....:.|:.:|  :|.:.....:.
 Frog    59 LDPKRLDGKTVLITGGTSGIGKETAIALAKRGARVIITNEDEEKGDTALRQI--KRESVSMNVKI 121

  Fly   179 AALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLT-LQL 242
            ..|::::|:|::.|.::..|....:|.||.||||.|: ...|.:|....|.|:||..|.|| |..
 Frog   122 MKLNMANLQSIREFCKDFVQKEKRLDILINNAGVPAV-LDWTDNGFSMCFGVNHLGTFLLTSLLT 185

  Fly   243 ETLFDYK-TRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRW 306
            |.|.... :|:|.::||.|::..|...:|. :::.|       :.:|..:||.||.|.||||::.
 Frog   186 ERLKSCSPSRVITVTSEVHKYQRLDFADLN-YNIVP-------LFSYCRSKLANVYFTQELARQI 242

  Fly   307 KQRGISVFSLHPGNMVSSDLSRNYWFYRL-LFAIVRPFTKSLQQAAATSIYCATANELTGLSGLY 370
            ::.|::..::|||.:|....|:....:|: ::.|...|..|..:.|.:.|:||.::::...:|.|
 Frog   243 ERHGVTSCAVHPGYVVGDWTSKFSVLFRIVMYVISSMFFISCLEGAQSVIHCAVSDDILQHNGGY 307

  Fly   371 FNNCFFCEPSKLSKSAALQQQLWKLSENLI 400
            |::|..|:....::...:.::||::||.::
 Frog   308 FSDCKPCKLRPHAQDTGIAKKLWEVSEIMV 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	85/283 (30%)
LOC100497142	XP_002932135.3	Mrp	7..>95	CDD:440255	18/35 (51%)
		Rossmann-fold NAD(P)(+)-binding proteins	66..333	CDD:473865	83/277 (30%)