Protein Alignment Wwox and rdh11

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: XP_031751072.1
• Gene: rdh11 / 100485470
• XenbaseID: XB-GENE-5943090
• Length: 327
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 103/313 - (32%)
• Similarity: 162/313 - (51%)
• Gaps: 24/313 - (7%)

  Fly    97 VAQVRQR--FD--SCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSS 157
            :.::|:|  :|  .||.:|.        |:||::||||.|||...|..||.....:|.|||:|..
 Frog    22 ILRLRRRKPWDPSKCSVSLA--------GKTAIVTGANTGIGKCVAMDLARRNARVILACRSRER 78

  Fly   158 AEAAIERIAQERPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVD 222
            .:.|:|.|  .|...........||.||:.||:.|.:.|.|....:|.||.|||...||::.|.:
 Frog    79 GQRALEEI--RRQTGNGAVLLEMLDTSSMASVRAFADRILQQEKRLDILINNAGASGLPHSMTAE 141

  Fly   223 GLETTFQVSHLSHFYLTLQLETLF--DYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSM 285
            |||.||..:||..|.||..|..|.  ...:||:.:||.:|:...:.:..|...::......|
 Frog   142 GLENTFATNHLGPFLLTNLLTGLMRKSAPSRIVFVSSFNHKNGEIHLSCLRGQNIRGFRPDY--- 203

  Fly   286 MAYNNAKLCNVLFAQELAQRWKQRGISVFSLHPGNMVSSDLSRNY-WFYRLLF-AIVRPFTKSLQ 348
             .||.:||.|::.|.|.|:|.:..|::|.||.|| :|.::..|.| .|.||:| :|...|.::.:
 Frog   204 -PYNCSKLMNIMCANEFARRLRGTGVTVTSLDPG-IVMTEAVRYYSIFIRLIFKSIGFFFFRTPE 266

  Fly   349 QAAATSIYCATANELTGLSGLYFN-NCFFCEPSKLSKSAALQQQLWKLSENLI 400
            :.|.::|:||.:.|..||:..|.: :|....||..::...:..:||:..|..:
 Frog   267 EGAVSTIFCAVSEEAEGLTEKYIDCDCMLALPSPAARDPPVTAKLWEACEQAV 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	97/285 (34%)
rdh11	XP_031751072.1	Rossmann-fold NAD(P)(+)-binding proteins	42..313	CDD:473865	95/277 (34%)