Protein Alignment Wwox and dhrs12lb

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: XP_002660947.4
• Gene: dhrs12lb / 100334077
• ZFINID: ZDB-GENE-131121-6
• Length: 325
• Species: Danio rerio
• Alignment Length: 285
• Identity: 87/285 - (30%)
• Similarity: 132/285 - (46%)
• Gaps: 32/285 - (11%)

  Fly   101 RQRFDSCSTALQVLHGKDLH----GRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAA 161
            |..|::.|.:..   .|||.    ||:.:|||||.|||..||.::|..|..:...|||:..||.|
Zfish    19 RSGFENASKSFA---AKDLDVSMVGRSFMITGANSGIGKATAMTIAKKGGTVHIVCRNKEKAERA 80

  Fly   162 IERIAQERPAARSRCRFA-ALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLE 225
            .|.|..   |:.:...|. .||||..|.|..|.|..|:..:.::.||.|||..........||||
Zfish    81 REEIVS---ASGNTMVFVHVLDLSESRKVWEFAEAFKKEHTSLNVLINNAGCMVNQREINSDGLE 142

  Fly   226 TTFQVSHLSHFYLTLQLETLFDYK--TRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAY 288
            ..|..:.|..:.||..|..|.:..  .|:|.:||     ..:.|:.|....|.....::.:.|.|
Zfish   143 KNFATNTLGVYILTKCLIPLLEKSRDPRVITVSS-----GGMLVQKLNPDDLQTERAQFDATMVY 202

  Fly   289 NNAKLCNVLFAQELAQRWKQRGISVFSLHPG----NMVSSDLSRNYWFYRLLFAIVRPFTKSLQQ 349
            ...|...|:..:..|:.:.:...||  :|||    ..|:|.:.:   ||:|:    |...:|.:|
Zfish   203 AQNKRQQVVMTEFWAKAYPKIHFSV--MHPGWADTPAVASAMPQ---FYQLM----RDRLRSAEQ 258

  Fly   350 AAATSIYCATAN-ELTGLSGLYFNN 373
            ::.|.|:.|.:. .:|..|||:|.:
Zfish   259 SSDTLIWLAMSRVTITFPSGLFFQD 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	81/261 (31%)
dhrs12lb	XP_002660947.4	None