DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment r2d2 and STAU1

DIOPT Version :9

Sequence 1:	NP_001162903.1	Gene:	r2d2 / 34066	FlyBaseID:	FBgn0031951	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001309861.1	Gene:	STAU1 / 6780	HGNCID:	11370	Length:	583	Species:	Homo sapiens

Alignment Length:	183	Identity:	46/183 - (25%)
Similarity:	84/183 - (45%)	Gaps:	22/183 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GNGRSKRDAKHLAASNILRKIQLLPGIHGLMKDSTVGDLDEELTNLNRDMVKELRDYCVRREMPL 111
            |.|::::.|||.||:..||.:|..|    |.:...|...:.|..|||:..:.::.:..::|.:|:
Human   140 GKGKTRQAAKHDAAAKALRILQNEP----LPERLEVNGRESEEENLNKSEISQVFEIALKRNLPV 200

  Fly   112 -----PCIEVVQQSGTPSAPEFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISSNSDNLRPD 171
                 |..:|.::||.|....||...||...|..|:...||.:::.|||.:|..:.........:
Human   201 NFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVE 265

  Fly   172 QMQVASTSKLK-VVDMEESME------------ELEALRRKKFTTYWELKEAG 211
            :::.....|.| :|..:.|.|            :::..:::|...|..|.|.|
Human   266 RVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERG 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
r2d2	NP_001162903.1	DSRM	6..67	CDD:238007	9/19 (47%)
r2d2	NP_001162903.1	DSRM	95..158	CDD:238007	18/67 (27%)
STAU1	NP_001309861.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..55
		DSRM	186..256	CDD:214634	19/69 (28%)
		DSRM	292..358	CDD:238007	5/27 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	366..403
		Staufen_C	454..563	CDD:293091
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810