DRSC/TRiP Functional Genomics Resources

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Protein Alignment r2d2 and STAU1

DIOPT Version :10

Sequence 1:NP_609152.1 Gene:r2d2 / 34066 FlyBaseID:FBgn0031951 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_001309861.1 Gene:STAU1 / 6780 HGNCID:11370 Length:583 Species:Homo sapiens


Alignment Length:183 Identity:46/183 - (25%)
Similarity:84/183 - (45%) Gaps:22/183 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 GNGRSKRDAKHLAASNILRKIQLLPGIHGLMKDSTVGDLDEELTNLNRDMVKELRDYCVRREMPL 111
            |.|::::.|||.||:..||.:|..|    |.:...|...:.|..|||:..:.::.:..::|.:|:
Human   140 GKGKTRQAAKHDAAAKALRILQNEP----LPERLEVNGRESEEENLNKSEISQVFEIALKRNLPV 200

  Fly   112 -----PCIEVVQQSGTPSAPEFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISSNSDNLRPD 171
                 |..:|.::||.|....||...||...|..|:...||.:::.|||.:|..:.........:
Human   201 NFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVE 265

  Fly   172 QMQVASTSKLK-VVDMEESME------------ELEALRRKKFTTYWELKEAG 211
            :::.....|.| :|..:.|.|            :::..:::|...|..|.|.|
Human   266 RVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERG 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
r2d2NP_609152.1 DSRM 6..68 CDD:214634 9/20 (45%)
DSRM_SF 102..158 CDD:380679 18/60 (30%)
STAU1NP_001309861.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..55
DSRM_STAU1_rpt2 82..146 CDD:380710 2/5 (40%)
DSRM_SF 183..255 CDD:444671 19/71 (27%)
DSRM_STAU1_rpt4 282..367 CDD:380714 7/37 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 366..403
Staufen_C 454..563 CDD:465131
Blue background indicates that the domain is not in the aligned region.

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