DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment santa-maria and CG7227

DIOPT Version :9

Sequence 1:	NP_609121.2	Gene:	santa-maria / 34024	FlyBaseID:	FBgn0025697	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	195/530 - (36%)
Similarity:	299/530 - (56%)	Gaps:	29/530 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 IFGFCLGLFGILCGMFWVDLFDWIMHKEMALAPDTRVYENWKSPPIDLSLDIYLYNWTNPEDFGN 85
            :.|..|..|.:...::...:..|::...|.|.|.|.:...|:||.:|:::|:|::||||.|.|.:
  Fly    12 VLGLLLASFSLFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNWTNSEKFSD 76

  Fly    86 LSTKPILEQVGPYRFIERPDKVDIHWHPENASVTYRRRSLFYFDAAGSNGSLDDEITTLNAVALS 150
            .:.||..|::|||||.||..||::.||.||::|:|||||.|.||...|.|...|.|...|.:.:.
  Fly    77 PTVKPRFEELGPYRFTERMQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRPTDPIVAPNLLIVG 141

  Fly   151 AAATAKYWPPVKRSLVDVGLKMYGAEMSVQKSIDELLFTGYNDAMIDVA-MAMPIFGDEVKVPFD 214
            .......|.|:.|||:.:.|.:||.|.::.:...:.:|.|::..||.:: |..|....|:|.|::
  Fly   142 LYQKMVMWSPMLRSLMLLALNIYGKEQAMIRPASDWMFDGFDTPMIKMSKMVPPSLVPEMKFPYE 206

  Fly   215 KFGWFYTRNGSADLTGVFNVFTGADQLAKLGQMHSWNYQENTGFFDSYCGMTNGSAGEFQPQHLK 279
            |.|:.|.||||.::.|..||:||.|:..||||:..|.| .|.......|.: .||||||.|..|.
  Fly   207 KIGYAYPRNGSMEIYGHHNVYTGRDEFQKLGQIARWRY-NNVTEASPRCKL-KGSAGEFHPIPLV 269

  Fly   280 PGDSVGLFTPDMCRTIPLDYVETVDIEGLEGYKFSGGPRSVDNGTQYPENLCFCGGQC--VPSGV 342
            .|..:..|.||:||.:.:||..|...||::.:.:.|..|::.|||..|:|.|:|...|  |.||:
  Fly   270 KGRPISYFLPDLCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPDNSCYCQDNCQEVRSGL 334

  Fly   343 MNISSCRFGSPVFMSYPHFFNADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIPLEVAARFQVNML 407
            :|||||.:|:|||.||||||.|||||.:||||:.|::..||..::::|.||:.||:.||...|:|
  Fly   335 LNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPKTGMVLEIKARIMANLL 399

  Fly   408 VEPIQGISLYTGIPRIFFPLVWFEQKVRITPDMADQLKVLPIVMLSGHIFAGICLIVGITLLCWT 472
            |||...: :|....|.||||:|.:..||||.|:...:|::||:...|.|...:.:::|:.::.|.
  Fly   400 VEPKTHL-IYRTARRTFFPLIWADYNVRITDDLLVYVKLMPILEFVGKICGILGVVLGLLMVFWY 463

  Fly   473 PVQILLASCRNRRYDLRTKTKTNGQYKSRSQFSSAEELKSKASTLVCEKSVKGSPDSSPLLEKGR 537
            |.|::.......:.:: :..:||         ||.|.:|:            ...:.|||| ||.
  Fly   464 PHQMIWQKSLMHKIEI-SSIETN---------SSLEPVKN------------NDVEDSPLL-KGL 505

  Fly   538 KPTIIKSQTG 547
            :....|...|
  Fly   506 QYAAAKDGAG 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	179/453 (40%)
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	178/452 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450676
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1.030639	Normalized mean entropy	S6187
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0007610
OrthoInspector	1	1.000	-	-		mtm4750
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	9	8.800