DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment santa-maria and ninaD

DIOPT Version :9

Sequence 1:	NP_609121.2	Gene:	santa-maria / 34024	FlyBaseID:	FBgn0025697	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_724087.1	Gene:	ninaD / 326160	FlyBaseID:	FBgn0002939	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	469	Identity:	138/469 - (29%)
Similarity:	232/469 - (49%)	Gaps:	30/469 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 IGIFGFCLGLFGILCGMFWVDLFDWIMHKEMALAPDTRVYENWKSPPIDLSLDIYLYNWTNPEDF 83
            :|.|....||..|:|   |....|..:.|.:.|.|.::.:|.|:..||.:.:.:||:||||..|.
  Fly    18 LGTFFAVSGLLAIIC---WPGFIDSGIMKALPLTPTSKTFEKWEELPIPVYVYMYLWNWTNAADV 79

  Fly    84 GNLSTKPILEQVGPYRFIERPDKVDIHWHPENASVTYRRRSLFYFDAAGSNGSLDDEITTLNAVA 148
            .....|||..|:|||.:.|...|:|:.|| :|.:||:..|..::::...|.|...|.||..:..:
  Fly    80 QANGVKPIFAQLGPYVYREERKKMDLEWH-DNGTVTFNPRRTWFWEEELSGGKQTDLITAPHLPS 143

  Fly   149 LSAAATAKYWPPVKRSLVDVGLKMYGAEMSVQKSIDELLFTGYNDAMIDVAMAM--PIFGDEVKV 211
            |:|:...:......:.:.:..|...|..:.|..:..|.||..:.|..:..||.:  |:.   .|:
  Fly   144 LAASNQMRNSNVFLKFMFNEALNANGGHLFVTHTAAEWLFESFYDEFLHYAMTLNNPLV---PKI 205

  Fly   212 PFDKFGWFYTRNGSADLTGVFNVFTGADQLAKLGQMHSWNYQENTGFFDSYCGMTNGSAGE-FQP 275
            ..|.|.||..||||.|..|.|.|.||...:.::|::..|..|.:||::|..||..|||..: |.|
  Fly   206 ESDHFAWFLNRNGSKDFEGPFTVHTGVGDIKEMGEIKYWKGQNHTGWYDGECGRLNGSTTDLFVP 270

  Fly   276 QHLKPGDSVGLFTPDMCRTIPLDYV-ETVDIEGLEGYKFSGGPRSVDNGTQYPENLCFC-----G 334
            ...|. .::.:|.||.||.|.|::. ::..|:|:.|:|:...|.:.|||.......|:|     .
  Fly   271 DEPKE-KALTIFIPDTCRIINLEFTGQSETIQGITGWKYEITPNTFDNGQINGNAKCWCPLERQP 334

  Fly   335 GQCVPSGVMNISSCRFGSPVFMSYPHFFNADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIPLEVA 399
            ..|..:|..::..|..|.|:::|..||..||..|...:.|.:||...:.||::::...|:||:|.
  Fly   335 DNCPATGATDLGPCADGVPMYLSADHFMYADESYGSTISGYNPNYDQNNFYIIMERKMGVPLKVN 399

  Fly   400 ARFQVNMLVEPIQGISLYTGIPRIFFPLVWFEQKVRITPDMADQLKV---LPIVMLSGHIFAGI- 460
            |...:.:.:||...|.:..|:|..:.||.....:..|...:|.:|::   ||.:   |. :.|:
  Fly   400 ANVMITLYIEPDSVIDILKGLPSFYAPLFTTASRAEIDEALASELRLALNLPAI---GR-YTGVG 460

  Fly   461 -----CLIVGITLL 469
                 |:::.:.:|
  Fly   461 FLCLGCILIAVGIL 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	136/465 (29%)
ninaD	NP_724087.1	CD36	19..474	CDD:279474	137/466 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450681
Domainoid	1	1.000	248	1.000	Domainoid score	I2091
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	251	1.000	Inparanoid score	I3140
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0007610
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	9	8.900