Protein Alignment santa-maria and Scarb2

DIOPT Version :10

• Sequence 1: NP_609121.2
• Gene: santa-maria / 34024
• FlyBaseID: FBgn0025697
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_446453.1
• Gene: Scarb2 / 117106
• RGDID: 621882
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 460
• Identity: 130/460 - (28%)
• Similarity: 232/460 - (50%)
• Gaps: 49/460 - (10%)

  Fly    42 DWIMHKEMALAPDTRVYENWKSPPIDLSLDIYLYNWTNPEDF--GNLSTKPILEQVGPYRFIERP 104
            |..:.|.|.|...|:|:::|:.||:.:.:..|.:|.||||:.  |.:   |:||:||||.:.|..
  Rat    34 DQTIEKNMVLQNGTKVFDSWEKPPLPVYIQFYFFNVTNPEEILQGEI---PLLEEVGPYTYRELR 95

  Fly   105 DKVDIHWHPENASVTYRRRSLFYFDAAGSNGS-LDDEITTLNAVALSAAATAKYWPPVKRSLVDV 168
            :|.::.:.....:::......:.|:...|.|. ..|.|.|:|...|:....|:  .|..|.:::.
  Rat    96 NKANVQFGENGTTISAVTNKAYIFERNQSVGDPTVDLIRTINIPLLTVVEMAQ--QPFLREIIEA 158

  Fly   169 GLKMYGAEMSVQKSIDELLFTGYNDAMIDVAMAMPIFGDEVKVPFDKFGWFYTRNGSADLTGVFN 233
            .||.|...:.|..::.|||: ||.|   :|...:.||..:|.   ..||.||.|||:.|  |.:.
  Rat   159 MLKAYQQTLFVTHTVHELLW-GYKD---EVLSLVHIFRPDVS---PNFGLFYERNGTND--GEYV 214

  Fly   234 VFTGADQLAKLGQMHSWNYQENTGFFDS-YCGMTNGSAGE-FQPQHLKPGDSVGLFTPDMCRTIP 296
            ..||.|......::..||.:.:..::.: .|.|.||:.|: |.|. :...:::.:|..|.||::.
  Rat   215 FLTGEDNYLNFTKIVEWNGKTSLDWWTTDTCNMINGTDGDSFHPL-ISKDETLYIFPSDFCRSVY 278

  Fly   297 LDYVETVDIEGLEGYKFSGGPRSVDNGTQYPENLCFC--GGQCVPSGVMNISSCRFGSPVFMSYP 359
            :.:....::|||..:::......:.|.:   ||..||  .|.|:.:||:|:|.|:.|:|:.||:|
  Rat   279 ITFSSFENVEGLPAFRYKVPAEILANSS---ENAGFCIPEGNCMDAGVLNVSICKNGAPIIMSFP 340

  Fly   360 HFFNADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIPLEVAARFQVNMLVEPIQGISLYTGIPRIF 424
            ||:.||..:...::|:.||:::||.::.:.|.|||.|..|.|||:|..|:.:........|..:.
  Rat   341 HFYQADEKFVSAIKGMRPNKEEHESFVDINPLTGIILRGAKRFQINTYVKKLDDFVETGNIRTMV 405

  Fly   425 FPLVWFEQKVRITPDMADQLKV----------LPIVMLSGHIFAGICLIVGITLLCWTPVQILLA 479
            ||:::..:.|.|..:.|.|||.          :|.::::..:|.|:       :..|       .
  Rat   406 FPVMYLNESVLIDKETASQLKSVINTTLIVTNIPYIIMALGVFFGL-------IFTW-------L 456

  Fly   480 SCRNR 484
            :||.:
  Rat   457 ACRGQ 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
santa-maria	NP_609121.2	CD36	21..476	CDD:460076	128/450 (28%)
Scarb2	NP_446453.1	CD36	28..457	CDD:460076	128/454 (28%)
		Important for interaction with GBA1. /evidence=ECO:0000250	155..191		11/39 (28%)