Protein Alignment Wnt6 and WNT10B

DIOPT Version :10

• Sequence 1: NP_609108.3
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_003385.2
• Gene: WNT10B / 7480
• HGNCID: 12775
• Length: 389
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 136/407 - (33%)
• Similarity: 194/407 - (47%)
• Gaps: 76/407 - (18%)

  Fly    29 LDPNLMCKKTRRLRGKLAEICRHD-----SALLKEIIINGINLGFRECEFQFRNRRWNCTVLRKS 88
            |..|.:|.....|..:...:|..:     |||      .|:::...||:.|.|::||||:.|...
Human    42 LTANTVCLTLSGLSKRQLGLCLRNPDVTASAL------QGLHIAVHECQHQLRDQRWNCSALEGG 100

  Fly    89 MR-----KILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAAT 148
            .|     .||.|..||:.|..::.||||.:||..||::|:||.|.|.   .:.:|.|.::
Human   101 GRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCG---WKGSGEQDRL----- 157

  Fly   149 AEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNN-ASTMTDIAPVEHRGGRNRRPGGRRGRRKFW 212
                     :|.:|:          .|.|||..: ..::....|     |.:..||
Human   158 ---------RAKLLQ----------LQALSRGKSFPHSLPSPGP-----GSSPSPG--------- 189

  Fly   213 DNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLEC 277
                 |:..||||||:.:::||.:.||.|||:::..|  |:...::.|||..||..:.:.::.:|
Human   190 -----PQDTWEWGGCNHDMDFGEKFSRDFLDSREAPR--DIQARMRIHNNRVGRQVVTENLKRKC 247

  Fly   278 KCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLRN-DGNSFMPESPHARPAN-KYQLV 340
            ||||.||||..||||...|.||.|...||:|...|..:...| :..:|   .|..||.. ..:||
Human   248 KCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAF---QPRLRPRRLSGELV 309

  Fly   341 FADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQT---NCKCVFKWC 402
            :.:.|||||..:...|:.||:||.||.||...|.|..|||.|||.   |..||   .|.|.|.||
Human   310 YFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHN---VLRQTRVERCHCRFHWC 371

  Fly   403 CEVTCEKCLEHRAVNTC 419
            |.|.|::|.....||.|
Human   372 CYVLCDECKVTEWVNVC 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_609108.3	Wnt_Wnt6	29..420	CDD:381712	136/407 (33%)
WNT10B	NP_003385.2	Wnt_Wnt10b	45..389	CDD:381730	135/404 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..197		7/44 (16%)