Protein Alignment Wnt6 and WNT8B

DIOPT Version :10

• Sequence 1: NP_609108.3
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_003384.2
• Gene: WNT8B / 7479
• HGNCID: 12789
• Length: 351
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 121/361 - (33%)
• Similarity: 159/361 - (44%)
• Gaps: 95/361 - (26%)

  Fly    63 GINLGFRECEFQFRNRRWNC--TVLRKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLV 125
            |...|..||::||...||||  ..|:.|....|...:|||.||:||::|||.|.:|:.|::|...
Human    46 GAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRSANRETAFVHAISSAGVMYTLTRNCSLGDFD 110

  Fly   126 ECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIA 190
            .|.||.:...:.|||
Human   111 NCGCDDSRNGQLGGQ-------------------------------------------------- 125

  Fly   191 PVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGT 255
                                          .|.||||||||.||...|:.|:||.:..:  |...
Human   126 ------------------------------GWLWGGCSDNVGFGEAISKQFVDALETGQ--DARA 158

  Fly   256 LVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKV-TLRN 319
            .:..|||.|||.|::..|:..|||||:|||||.:||||::|.||||...|:::|.:|.|| .|:.
Human   159 AMNLHNNEAGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDLLQG 223

  Fly   320 DGNSFMPESPHA---RPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDR-----CD 376
            .|||.......|   |..:..:||..:||||:|..|...|.|||:||||........|     |.
Human   224 AGNSAAGRGAIADTFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRRGRALGRWERRSCR 288

  Fly   377 RLC--CNRGHTRRIVEEQTNCKCVFKWCCEVTCEKC 410
            |||  |......|..|..::|.|.|.|||.|.||:|
Human   289 RLCGDCGLAVEERRAETVSSCNCKFHWCCAVRCEQC 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_609108.3	Wnt_Wnt6	29..420	CDD:381712	121/361 (34%)
WNT8B	NP_003384.2	Wnt_Wnt8b	30..334	CDD:381726	121/361 (34%)