Protein Alignment Wnt6 and WNT8A

DIOPT Version :10

• Sequence 1: NP_609108.3
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001287867.1
• Gene: WNT8A / 7478
• HGNCID: 12788
• Length: 386
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 123/365 - (33%)
• Similarity: 170/365 - (46%)
• Gaps: 100/365 - (27%)

  Fly    63 GINLGFRECEFQFRNRRWNC--TVLRKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLV 125
            |...|..||:|||...||||  ..|:.|....|...:|||.|::||::|||.|.:||.|:||...
Human    64 GAQSGIEECKFQFAWERWNCPENALQLSTHNRLRSATRETSFIHAISSAGVMYIITKNCSMGDFE 128

  Fly   126 ECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIA 190
            .|.||
Human   129 NCGCD------------------------------------------------------------ 133

  Fly   191 PVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGT 255
                 |..|.:.||.               .|.||||||||.||.|.|::|:|:.::.:  |...
Human   134 -----GSNNGKTGGH---------------GWIWGGCSDNVEFGERISKLFVDSLEKGK--DARA 176

  Fly   256 LVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTL--- 317
            |:..|||.|||||:|..|:..|||||:||||:::||||::..|||:...|:.:||.|.|:.:
Human   177 LMNLHNNRAGRLAVRATMKRTCKCHGISGSCSIQTCWLQLAEFREMGDYLKAKYDQALKIEMDKR 241

  Fly   318 -RNDGNS----FMPESPHARPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDR--- 374
             ...|||    ::|..... |:.:.:|:|.::|||:||.||..|..||:||||...|..:.|
Human   242 QLRAGNSAEGHWVPAEAFL-PSAEAELIFLEESPDYCTCNSSLGIYGTEGRECLQNSHNTSRWER 305

  Fly   375 --CDRLC--CNRGHTRRIVEEQTNCKCVFKWCCEVTCEKC 410
              |.|||  |......|..|..::|.|.|:|||.|.|::|
Human   306 RSCGRLCTECGLQVEERKTEVISSCNCKFQWCCTVKCDQC 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_609108.3	Wnt_Wnt6	29..420	CDD:381712	123/365 (34%)
WNT8A	NP_001287867.1	Wnt_Wnt8a	49..349	CDD:381725	123/365 (34%)