Protein Alignment Wnt6 and WNT7A

DIOPT Version :10

• Sequence 1: NP_609108.3
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_004616.2
• Gene: WNT7A / 7476
• HGNCID: 12786
• Length: 349
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 139/405 - (34%)
• Similarity: 192/405 - (47%)
• Gaps: 98/405 - (24%)

  Fly    27 ILLDPNLMCKKTRRLRGKLAEIC--RHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVL--RK 87
            :.|..:::|.|...|..:...||  |.|:.:   :|..|..:|..||:|||||.||||:.|  |.
Human    30 VALGASIICNKIPGLAPRQRAICQSRPDAII---VIGEGSQMGLDECQFQFRNGRWNCSALGERT 91

  Fly    88 SMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAA 152
            ...|.|...|||..|..||.||||.:|:|.|||.|.|.:|.|||
Human    92 VFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDK--------------------- 135

  Fly   153 LERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKF 217
             |:|.|                                  .||
Human   136 -EKQGQ----------------------------------YHR---------------------- 143

  Fly   218 PEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGL 282
            .|| |:|||||.::.:|:..::||:||  |:.:.:..||:..|||.|||..:.:.|:|||||||:
Human   144 DEG-WKWGGCSADIRYGIGFAKVFVDA--REIKQNARTLMNLHNNEAGRKILEENMKLECKCHGV 205

  Fly   283 SGSCTVKTCWLKMPPFREVAGRLRDRYDSARKV----TLRNDGNSFM----PESPHARPANKYQL 339
            |||||.||||..:|.|||:...|:|:|:.|..|    ..||...:|:    |.| :.:|.:. .|
Human   206 SGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLS-YRKPMDT-DL 268

  Fly   340 VFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQTNCKCVFKWCCE 404
            |:.:.||::|..:..||::|||||.||.|:..:..||.:||.||:..........|.|.|.|||.
Human   269 VYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCY 333

  Fly   405 VTCEKCLEHRAVNTC 419
            |.|..|.|...:.||
Human   334 VKCNTCSERTEMYTC 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_609108.3	Wnt_Wnt6	29..420	CDD:381712	139/403 (34%)
WNT7A	NP_004616.2	Wnt_Wnt7a	32..349	CDD:381723	139/403 (34%)
		Disordered linker. /evidence=ECO:0000269|PubMed:30026314	238..266		7/28 (25%)