DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wnt6 and Wnt4

DIOPT Version :10

Sequence 1:NP_609108.3 Gene:Wnt6 / 34010 FlyBaseID:FBgn0031902 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_476972.2 Gene:Wnt4 / 34007 FlyBaseID:FBgn0010453 Length:539 Species:Drosophila melanogaster


Alignment Length:397 Identity:113/397 - (28%)
Similarity:170/397 - (42%) Gaps:125/397 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 NLMCKKTRRLRGKLAEICRHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVLRKSMRKILMRD 96
            |..|:|...|.|.|:|..|               |....||.|||..||||::..:..|.|..:.
  Fly   250 NHQCRKETGLPGTLSEARR---------------LATTHCEEQFRYDRWNCSIETRGKRNIFKKL 299

  Fly    97 SRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAM 161
            .:||.||:|:|||.:|:::.:||..|::.:|||                                
  Fly   300 YKETAFVHALTAAAMTHSIARACAEGRMTKCSC-------------------------------- 332

  Fly   162 LRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQ-WEWG 225
                                        .|.:|    ||                  |.| ::||
  Fly   333 ----------------------------GPKKH----NR------------------EAQDFQWG 347

  Fly   226 GCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKT 290
            ||:||:..|.|.:|.|||.  |....|..:.:..|::..|..|:...|..:|||||:||||::||
  Fly   348 GCNDNLKHGKRVTRSFLDL--RGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKT 410

  Fly   291 CWLKMPPFREVAGRLRDRYDSA-RKV----TLRNDGNSFM--PESPHARP-ANKY-QLVFADDSP 346
            ||.||..|...|..||.:|:.| ||.    ::|...:|.|  |:....:| .::| .|.:.:.||
  Fly   411 CWKKMADFNATATLLRQKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSP 475

  Fly   347 DFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQTNCKCVFK--WCCEVTCEK 409
            .:|..        |:.|:|    ...|.|..|||.||:|.::|::...|:|.|.  .||::.|:.
  Fly   476 SYCAV--------TKDRQC----LHPDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDY 528

  Fly   410 C--LEHR 414
            |  ||::
  Fly   529 CQRLENK 535

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wnt6NP_609108.3 Wnt_Wnt6 29..420 CDD:381712 113/397 (28%)
Wnt4NP_476972.2 Wnt_Wnt9 245..539 CDD:381715 113/397 (28%)

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