Protein Alignment Wnt6 and Wnt10b

DIOPT Version :10

• Sequence 1: NP_609108.3
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_035848.1
• Gene: Wnt10b / 22410
• MGIID: 108061
• Length: 389
• Species: Mus musculus
• Alignment Length: 406
• Identity: 134/406 - (33%)
• Similarity: 188/406 - (46%)
• Gaps: 74/406 - (18%)

  Fly    29 LDPNLMCKKTRRLRGKLAEICRHD-----SALLKEIIINGINLGFRECEFQFRNRRWNCTVLRKS 88
            |..|.:|.....|..:...:|...     |||      .|:::...||:.|.|::||||:.|...
Mouse    42 LTANTVCLTLSGLSKRQLGLCLRSPDVTASAL------QGLHIAVHECQHQLRDQRWNCSALEGG 100

  Fly    89 MR-----KILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAAT 148
            .|     .||.|..||:.|..::.||||.:||..||::|:||.|.|.   .:.:|.|.::.....
Mouse   101 GRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCG---WKGSGEQDRLRAKLL 162

  Fly   149 AEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWD 213
            ...||.| .:...:.|..|:....||                           ||
Mouse   163 QLQALSR-GKTFPISQPSPVPGSVPS---------------------------PG---------- 189

  Fly   214 NIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECK 278
                |:..||||||:.:::||.:.||.|||:::..|  |:...::.|||..||..:.:.::.:||
Mouse   190 ----PQDTWEWGGCNHDMDFGEKFSRDFLDSREAPR--DIQARMRIHNNRVGRQVVTENLKRKCK 248

  Fly   279 CHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLRN-DGNSFMPESPHARPAN-KYQLVF 341
            |||.||||..||||...|.||.:...||:|...|..:...| :..:|   .|..||.. ..:||:
Mouse   249 CHGTSGSCQFKTCWRAAPEFRAIGAALRERLSRAIFIDTHNRNSGAF---QPRLRPRRLSGELVY 310

  Fly   342 ADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQT---NCKCVFKWCC 403
            .:.|||||..:...|:.||:||.||.||...|.|..|||.|||.   |..||   .|.|.|.|||
Mouse   311 FEKSPDFCERDPTLGSPGTRGRACNKTSRLLDGCGSLCCGRGHN---VLRQTRVERCHCRFHWCC 372

  Fly   404 EVTCEKCLEHRAVNTC 419
            .|.|::|.....||.|
Mouse   373 YVLCDECKVTEWVNVC 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_609108.3	Wnt_Wnt6	29..420	CDD:381712	134/406 (33%)
Wnt10b	NP_035848.1	Wnt_Wnt10b	45..389	CDD:381730	133/403 (33%)