Protein Alignment Wnt4 and WNT4

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_011539899.1
• Gene: WNT4 / 54361
• HGNCID: 12783
• Length: 373
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 111/312 - (35%)
• Similarity: 165/312 - (52%)
• Gaps: 30/312 - (9%)

  Fly   247 RRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY----KETAFVH 307
            :||...|::...:..::....:||...|:.|||..|||||  |.....:|.|:.    :|.|||:
Human    73 QRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCS--TLDSLPVFGKVVTQGTREAAFVY 135

  Fly   308 ALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLR-GGDG 371
            |:::|.:..::.|||:.|.:.||.|....|....|.|||.||:||:.:|...::||:|:| ...|
Human   136 AISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKG 200

  Fly   372 DEVSEILR--HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIR 434
            ...|..|.  |::|.|.:|:.:.|..:||||||||||.:||||:.:..|......|::|::.|..
Human   201 ASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATE 265

  Fly   435 KAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAV--------TKDRQCLHP-- 489
            ..|     |:|.|||...|:..:.||...:  .|.|||.||.:|..        |:.|.|...
Human   266 VEP-----RRVGSSRALVPRNAQFKPHTDE--DLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSK 323

  Fly   490 --DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539
              |.|..||||||:.|..|:..|:|.|:|:  .||.:.|..||||...:.|:
Human   324 AIDGCELLCCGRGFHTAQVELAERCSCKFH--WCCFVKCRQCQRLVELHTCR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	110/310 (35%)
WNT4	XP_011539899.1	Wnt_Wnt4	65..373	CDD:381710	110/310 (35%)