Protein Alignment Wnt4 and wnt2

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_571025.1
• Gene: wnt2 / 30127
• ZFINID: ZDB-GENE-980526-416
• Length: 350
• Species: Danio rerio
• Alignment Length: 318
• Identity: 113/318 - (35%)
• Similarity: 167/318 - (52%)
• Gaps: 49/318 - (15%)

  Fly   259 LPGTLSEARRLATTH-----------------CEEQFRYDRWNCSIETRGKRNIFKKLY----KE 302
            :||.:::.|:|...|                 |:.|||..||||:...| :.|:|.:|.    :|
Zfish    42 IPGLINKQRQLCRQHPKVMQAIGAGIKNWIGECQHQFRTHRWNCNTMAR-EHNLFGRLLHRSSRE 105

  Fly   303 TAFVHALTAAAMTHSIARACAEGRMTKCSCGP--KKHNREAQD-FQWGGCNDNLKHGKRVTRSFL 364
            .|||:|:::|.|.:::.|||::|.:..|||.|  |..:|:|:. |.||||:|::.|..:.|:.|:
Zfish   106 AAFVYAISSAGMVYTLTRACSQGELENCSCDPGKKGSSRDAKGAFDWGGCSDHVDHAIKFTQVFI 170

  Fly   365 DLRGGDGDEVSEILR-HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQK 428
            |.:.....:...::. |::..|.:||...|..:||||||||||:::|||..||||..|...||:|
Zfish   171 DAKERKERDARALMNLHNNRAGRKAVKRFMNLECKCHGVSGSCNVRTCWLAMADFRQTGDYLRKK 235

  Fly   429 YNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYC--------AVTKDRQ 485
            ||.||:...||......|:.||      .|:|.::.   |.|.|.||.||        ..|..|.
Zfish   236 YNNAIQVVMNQYGTGFTSAYRM------LKRPNKND---LVYFEDSPDYCIWDHESGSVGTGGRV 291

  Fly   486 CLH----PDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539
            |..    .|:|..:||||||.|..|.:..||.|:|.  .||.:.|..||...:.:.||
Zfish   292 CNRTSRGTDSCEVMCCGRGYDTSRVSRTTKCECKFQ--WCCAVHCRDCQEEVDVHTCK 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	111/316 (35%)
wnt2	NP_571025.1	Wnt	34..347	CDD:393294	111/316 (35%)