Protein Alignment Wnt4 and Wnt3a

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_033548.1
• Gene: Wnt3a / 22416
• MGIID: 98956
• Length: 352
• Species: Mus musculus
• Alignment Length: 325
• Identity: 107/325 - (32%)
• Similarity: 160/325 - (49%)
• Gaps: 39/325 - (12%)

  Fly   240 CRYMPA-TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNC-----SIETRGKRNIFKK 298
            |..:|. ..:|...||....:..:::|..:.....|:.|||..||||     |:...|.  :..|
Mouse    42 CASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGP--VLDK 104

  Fly   299 LYKETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSF 363
            ..:|:|||||:.:|.:..::.|:||||....|.|..:......:.::||||:::::.|..|:|.|
Mouse   105 ATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREF 169

  Fly   364 LDLRGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQK 428
            .|.|....|..|.:.||::|.|.:|::|.|..||||||:||||.:||||....||......|:.|
Mouse   170 ADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDK 234

  Fly   429 YNEA----IRKAPNQRSMRQVSSSR---MKKPKQRRKKPQQSQYTTLYYLETSPSYCAV------ 480
            |:.|    :.|....|...:....|   .|.|.:|          .|.|.|.||::|..
Mouse   235 YDSASEMVVEKHRESRGWVETLRPRYTYFKVPTER----------DLVYYEASPNFCEPNPETGS 289

  Fly   481 --TKDRQC---LHP-DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539
              |:||.|   .|. |.|..||||||:..:..::.|||.|.|:  .||.:.|..|.|:.:.:.||
Mouse   290 FGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFH--WCCYVSCQECTRVYDVHTCK 352

  Fly   540  539
            Mouse   353  352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	103/318 (32%)
Wnt3a	NP_033548.1	Wnt_Wnt3_Wnt3a	39..352	CDD:381709	105/323 (33%)