Protein Alignment Wnt4 and Wnt3

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_033547.1
• Gene: Wnt3 / 22415
• MGIID: 98955
• Length: 355
• Species: Mus musculus
• Alignment Length: 326
• Identity: 111/326 - (34%)
• Similarity: 160/326 - (49%)
• Gaps: 41/326 - (12%)

  Fly   240 CRYMPA-TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNC-----SIETRGKRNIFKK 298
            |..:|. ..:|...||....:..:::|..:|....|:.|||..||||     |:...|.  :..|
Mouse    45 CGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGP--VLDK 107

  Fly   299 LYKETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSF 363
            ..:|:|||||:.:|.:..::.|:||||..|.|.|.........:.::||||:::...|..|:|.|
Mouse   108 ATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREF 172

  Fly   364 LDLRGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQK 428
            .|.|....|..|.:.:|::|.|...:...|..||||||:||||.:||||....||.|....|:.|
Mouse   173 ADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDK 237

  Fly   429 YNEA----IRKAPNQRSMRQVSSSRMK----KPKQRRKKPQQSQYTTLYYLETSPSYCAV----- 480
            |:.|    :.|  ::.|...|.:.|.|    ||...|         .|.|.|.||::|..
Mouse   238 YDSASEMVVEK--HRESRGWVETLRAKYALFKPPTER---------DLVYYENSPNFCEPNPETG 291

  Fly   481 ---TKDRQC---LHP-DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFC 538
               |:||.|   .|. |.|..||||||:.|:..|:.|||.|.|:  .||.:.|..|.|:.:.:.|
Mouse   292 SFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFH--WCCYVSCQECIRIYDVHTC 354

  Fly   539 K 539
            |
Mouse   355 K 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	107/319 (34%)
Wnt3	NP_033547.1	Wnt_Wnt3_Wnt3a	42..355	CDD:381709	109/324 (34%)