Protein Alignment Wnt4 and Wnt1

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_067254.1
• Gene: Wnt1 / 22408
• MGIID: 98953
• Length: 370
• Species: Mus musculus
• Alignment Length: 312
• Identity: 103/312 - (33%)
• Similarity: 163/312 - (52%)
• Gaps: 26/312 - (8%)

  Fly   246 TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY----KETAFV 306
            :|:|....|:..|:..::|...:.|...|:.|||..||||  .|....::|.|:.    :||||:
Mouse    65 SRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNC--PTAPGPHLFGKIVNRGCRETAFI 127

  Fly   307 HALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLRGGDG 371
            .|:|:|.:|||:||:|:||.:..|:|..::......|:.||||:||:..|:...|.|:| .|..|
Mouse   128 FAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLFGREFVD-SGEKG 191

  Fly   372 DEVSEILR-HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRK 435
            .::..::. |::|.|...|.|:|..:|||||:||||:::|||.::....|...:||.:::.|.|.
Mouse   192 RDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRV 256

  Fly   436 APNQRSMRQVSSSRMKK--PKQRRKKPQQSQYTTLYYLETSPSYC--------AVTKDRQCLHP- 489
            ....|...:.|.:.:.:  |:....||....  .|.|.|.||::|        |.|..|.|...
Mouse   257 LYGNRGSNRASRAELLRLEPEDPAHKPPSPH--DLVYFEKSPNFCTYSGRLGTAGTAGRACNSSS 319

  Fly   490 ---DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFC 538
               |.|..||||||:.|:..:..|:|.|.|:  .||.:.|..|......:.|
Mouse   320 PALDGCELLCCGRGHRTRTQRVTERCNCTFH--WCCHVSCRNCTHTRVLHEC 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	103/312 (33%)
Wnt1	NP_067254.1	Wnt_Wnt1	64..370	CDD:381707	103/312 (33%)