Protein Alignment Wnt4 and Wnt8a

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_033316.2
• Gene: Wnt8a / 20890
• MGIID: 107924
• Length: 354
• Species: Mus musculus
• Alignment Length: 312
• Identity: 92/312 - (29%)
• Similarity: 155/312 - (49%)
• Gaps: 34/312 - (10%)

  Fly   254 RKETGLPGTLSEA--RRLATTHCEEQFRYDRWNC-----SIETRGKRNIFKKLYKETAFVHALTA 311
            |.:..|..|.|.|  .::....|:.||.::||||     ...|   .|..:...:||:|:||:.:
Mouse    32 RPKAYLTYTASVALGAQIGIEECKFQFAWERWNCPEHAFQFST---HNRLRAATRETSFIHAIRS 93

  Fly   312 AAMTHSIARACAEGRMTKCSCGPKKHNRE-AQDFQWGGCNDNLKHGKRVTRSFLDLRGGDGDEVS 375
            ||:.:::.:.|:.|.:..|.|...::.:. ...:.||||:||::.|::::|.|:|......|..:
Mouse    94 AAIMYAVTKNCSMGDLENCGCDESQNGKTGGHGWIWGGCSDNVEFGEKISRLFVDSLEKGKDARA 158

  Fly   376 EILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRKAPNQR 440
            .:..|::..|..||.:.....|||||:|||||::|||.::|||......|:.||:.|::...::|
Mouse   159 LVNLHNNRAGRLAVRASTKRTCKCHGISGSCSIQTCWLQLADFRQMGNYLKAKYDRALKIEMDKR 223

  Fly   441 SMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYC--------AVTKDRQCL---------H 488
            .:|..:.:..:........|  |....|.:||.||.||        ..|:.|:||         .
Mouse   224 QLRAGNRAEGRWALTEAFLP--STEAELIFLEGSPDYCNRNASLSIQGTEGRECLQNARSASRRE 286

  Fly   489 PDNCGTLC--CGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFC 538
            ..:||.||  ||.....:..:.|..|.|.|.  .||.:.|..|:|:.::|:|
Mouse   287 QRSCGRLCTECGLQVEERRAEAVSSCDCNFQ--WCCTVKCGQCRRVVSRYYC 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	92/312 (29%)
Wnt8a	NP_033316.2	Wnt	31..337	CDD:393294	92/312 (29%)