Protein Alignment Wnt4 and wnt2

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_012815404.1
• Gene: wnt2 / 100038261
• XenbaseID: XB-GENE-486595
• Length: 365
• Species: Xenopus tropicalis
• Alignment Length: 334
• Identity: 117/334 - (35%)
• Similarity: 172/334 - (51%)
• Gaps: 35/334 - (10%)

  Fly   228 AVFTSQGQVGGPCRYMPA-TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRG 291
            ||.||.......|..:|. ..||...|::...:...:.......||.|:.|||:.||||:|..|
 Frog    32 AVVTSSSSSRVMCNNIPGLVTRQRQLCQRYPEIMQVIGLGAVEWTTECQHQFRHHRWNCNIMER- 95

  Fly   292 KRNIFKKLY----KETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQD---FQWGGC 349
            .:::|.||.    :|:|||||:::|.:..:|.|||::|.:..|||.|.|.......   |.|.||
 Frog    96 DQSLFGKLILRSSRESAFVHAISSAGIVFAITRACSQGELKSCSCDPTKKGSSKDSKGGFDWDGC 160

  Fly   350 NDNLKHGKRVTRSFLDLRGGDGDEVSEILR-HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWK 413
            :||:.:|.|..|:|:|.:...|.:...::. |:::.|.:||...|..:||||||||||:::|||.
 Frog   161 SDNIDYGIRFARTFVDAKERKGKDARALMNLHNNKAGRKAVKRFMKQECKCHGVSGSCTVRTCWM 225

  Fly   414 KMADFNATATLLRQKYNEAIRKAPNQRSMR-QVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSY 477
            .|.||..:...||:|||.||:...||.... .|:::|.|||..          ..|.|.|.||.|
 Frog   226 AMGDFRKSGDYLRRKYNGAIQVVMNQDGTGFTVANTRFKKPTN----------NDLVYFENSPDY 280

  Fly   478 CAVTKD--------RQCLHP----DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQ 530
            |...:|        |.|...    |:|..:||||||.|..:.::.||.|:|:  .||.:.|..|.
 Frog   281 CVRDRDVGSLGTAGRICNQTSRGMDSCEVMCCGRGYDTARITKMSKCECKFH--WCCSVRCKDCI 343

  Fly   531 RLENKYFCK 539
            ...:.:.||
 Frog   344 ETVDIHTCK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	109/315 (35%)
wnt2	XP_012815404.1	Wnt_Wnt2	41..352	CDD:381719	111/323 (34%)