Protein Alignment mEFG1 and SNU114

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_012748.1
• Gene: SNU114 / 853681
• SGDID: S000001656
• Length: 1008
• Species: Saccharomyces cerevisiae
• Alignment Length: 888
• Identity: 176/888 - (19%)
• Similarity: 310/888 - (34%)
• Gaps: 258/888 - (29%)

  Fly    12 NTLRLRALKSLGKAGYSSHAKFSEHKPIERIRNIGISAHIDSGKTTLTERILFYT-GRIAEMHEV 75
            :|:..:..|::.|..|:.....|.....|||.|:|:...:.||||:|.:.::..: .||.:|.:
Yeast   103 HTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKRIPDMSK- 166

  Fly    76 RGKDNVG------ATMDSMELERQRGITIQSAATYTLWKDTN-----INIIDTPGHVDFTVEVER 129
                ||.      ..:|:::.|..||::|:...:..|..|..     ||.:|.||||:|..|...
Yeast   167 ----NVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGHVNFMDETAV 227

  Fly   130 ALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRL-------GSNPYRVLSQMR 187
            ||...|..::|:..|.||......:.:|..:.||.....|||||||       ..:.|..|:.:.
Yeast   228 ALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILDLKLPPMDAYLKLNHII 292

  Fly   188 SKMN------------HNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLDEIP----- 235
            :.:|            :|..|....:|.....|..|.       |:........::|:..
Yeast   293 ANINSFTKGNVFSPIDNNIIFASTKLGFTFTIKEFVS-------YYYAHSIPSSKIDDFTTRLWG 350

  Fly   236 ---------QDMRVESLERRQELIEHL------------------------SNADETLGE--LFL 265
                     :....|::|:....:|.:                        ||....|.:  |..
Yeast   351 SVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFSYALSMEKDKLKNLLRSNFRVNLSQEALQY 415

  Fly   266 EEKPFTEDDIKAALRR-----TCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFI 325
            :.:||.:..::...|:     ..|.|.:.|.            .|.|....:|..||:
Yeast   416 DPQPFLKHVLQLIFRQQTGLVDAITRCYQPF------------ELFDNKTAHLSIPGK------- 461

  Fly   326 EKEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFG--QLTYLRCYQGVLRKGDNIFNARTNK-KV 387
                ..||..:             .|..|:...:|  :.:.:|.|.|:|::||.:....|:: :.
Yeast   462 ----STPEGTL-------------WAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSES 509

  Fly   388 RIARLVRLH-------SNQMED-----------------------VNEVYAGDIFALFGVDCA-- 420
            |..|  :||       ||:.||                       |:|.:.|.|..:.|:..|
Yeast   510 RQKR--QLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKGISSAYI 572

  Fly   421 -SGDTFTTNPKNNLSMESIFVP-----EPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFD 479
             |...::...|.::.....|.|     |.|..:.::|...::......|:.:.:|..|......:
Yeast   573 KSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNKISKYYPGVIIKVE 637

  Fly   480 NDVKETLVSGMGELHLEIYAQRMEREYG-CPVTLGKPKVAF----------------------RE 521
             :..|.::.|.|||:::.....:...|. ..:.:..|...|                      .|
Yeast   638 -ESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCSNESFASIPVSNSISRLGEE 701

  Fly   522 TLVG--------PCEFDYLH--KKQSGGSGQYA-RIIGVMEPLPPNQNTLLEFV------DETVG 569
            .|.|        |.:...:.  .:.:.|.||.. .|.|:|:    |...|.:.:      |....
Yeast   702 NLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGIMD----NPRKLSKILRTEYGWDSLAS 762

  Fly   570 TNV--------------PKQFVPGVEKGYREM--------AEKGMLSGHKLSGIRFRL------Q 606
            .||              |.:..|.:...|:|.        .::|.|:...:.|::::|      .
Yeast   763 RNVWSFYNGNVLINDTLPDEISPELLSKYKEQIIQGFYWAVKEGPLAEEPIYGVQYKLLSISVPS 827

  Fly   607 DGGHHIVDSSELAFMLAA--HGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGI- 668
            |....::.|..:..|..|  .|.:..:     ..:||||..|::|........|...:.||.|.
Yeast   828 DVNIDVMKSQIIPLMKKACYVGLLTAI-----PILLEPIYEVDITVHAPLLPIVEELMKKRRGSR 887

  Fly   669 ------ITGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKG 705
                  :.||...|    |..:||:.:..|:..:||.||.|.|
Yeast   888 IYKTIKVAGTPLLE----VRGQVPVIESAGFETDLRLSTNGLG 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	171/862 (20%)
SNU114	NP_012748.1	PRK13351	121..992	CDD:481252	172/870 (20%)