Protein Alignment mEFG1 and MEF1

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_013170.1
• Gene: MEF1 / 850758
• SGDID: S000004059
• Length: 761
• Species: Saccharomyces cerevisiae
• Alignment Length: 698
• Identity: 380/698 - (54%)
• Similarity: 508/698 - (72%)
• Gaps: 13/698 - (1%)

  Fly    41 RIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYT 105
            ::|||||||||||||||.|||:|:||.||..:|||||:|||||.||||:|||::||||||||||.
Yeast    69 KLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATYC 133

  Fly   106 LW----KDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCL 166
            .|    |:.:.|:||||||:|||:|||||||||||||||:|||.||||||:||:|||:|||||.:
Yeast   134 SWDKEGKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRV 198

  Fly   167 AFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRL 231
            .||||:||:||:|:|.:.|:.||:...||.:|:|||.||:..|:|||:...|||.:|::|..|..
Yeast   199 TFINKMDRMGSDPFRAIEQLNSKLKIPAAAVQIPIGSESSLSGVVDLINRVAIYNKGDNGEIIEK 263

  Fly   232 DEIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTA 296
            ..:|::::....|:||.|||.|::.|:.:.|:|||||..|...||.|:||:.|.|:|||||:|:|
Yeast   264 GPVPENLKPLMEEKRQLLIETLADVDDEMAEMFLEEKEPTTQQIKDAIRRSTIARSFTPVLMGSA 328

  Fly   297 LKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFGQ 361
            |.|.|:||:|||::||||||.||.|...  ....:..||.|.||  .:.||||||||||.|::||
Yeast   329 LANTGIQPVLDAIVDYLPNPSEVLNTAL--DVSNNEAKVNLVPA--VQQPFVGLAFKLEEGKYGQ 389

  Fly   362 LTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFT 426
            |||:|.|||.||||:.|.|.:|.|||::|||||:||::||||:||.:|:|.|.||:||||||||
Yeast   390 LTYVRVYQGRLRKGNYITNVKTGKKVKVARLVRMHSSEMEDVDEVGSGEICATFGIDCASGDTF- 453

  Fly   427 TNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMG 491
            |:.....||.|::||:.|||::|.| |:||..|||||:.||.||||||...||.:.|||::||||
Yeast   454 TDGSVQYSMSSMYVPDAVVSLSITP-NSKDASNFSKALNRFQKEDPTFRVKFDPESKETIISGMG 517

  Fly   492 ELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPP- 555
            |||||||.:||.|||......|||:|::||::..|.:|||.|||||||:|||.|:||.:.|:..
Yeast   518 ELHLEIYVERMRREYNVDCVTGKPQVSYRESITIPADFDYTHKKQSGGAGQYGRVIGTLSPVDDI 582

  Fly   556 NQNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAF 620
            .:..:.|  ...||..:|.:::....||:.|:.|||.|.||::..::..:.||..|.|||:||:|
Yeast   583 TKGNIFE--TAIVGGRIPDKYLAACGKGFEEVCEKGPLIGHRVLDVKMLINDGAIHAVDSNELSF 645

  Fly   621 MLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEV 685
            ..|...|.::.|......|:||||.|.||:|.||||.|:|.|:|...:|..||.....||:.||.
Yeast   646 KTATMSAFRDAFLRAQPVIMEPIMNVSVTSPNEFQGNVIGLLNKLQAVIQDTENGHDEFTLKAEC 710

  Fly   686 PLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQ 733
            .|:.|||:|..||:||||||||::|:|.|:|..|.||.:::.::|:.|
Yeast   711 ALSTMFGFATSLRASTQGKGEFSLEFSHYAPTAPHVQKELISEFQKKQ 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	378/694 (54%)
MEF1	NP_013170.1	FusA	68..759	CDD:440248	380/698 (54%)