Protein Alignment mEFG1 and gfm2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001071013.1
• Gene: gfm2 / 558184
• ZFINID: ZDB-GENE-060201-3
• Length: 762
• Species: Danio rerio
• Alignment Length: 774
• Identity: 256/774 - (33%)
• Similarity: 398/774 - (51%)
• Gaps: 75/774 - (9%)

  Fly     1 MSLITRLLTG------NNTLRLRALKSLGKAGYS------SHAKFSEHKPIERIRNIGISAHIDS 53
            :||...:|.|      |.:|:....:...|..||      ...:...:..|.:||||||.||||:
Zfish     3 LSLTFPVLRGCTGHLVNRSLQAPRWRVTWKRSYSLLQDEVKSLRTVVNPDISKIRNIGIMAHIDA 67

  Fly    54 GKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTP 118
            ||||.|||:|:|:|....:.:|...|.|   .|.|..||:|||||||||....|||..||:||||
Zfish    68 GKTTTTERMLYYSGYTRALGDVDDGDTV---TDYMAQERERGITIQSAAVTFDWKDYRINLIDTP 129

  Fly   119 GHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVL 183
            ||||||:|||||||||||||.|..|..||::||:||.||.:::.:||:.|:||:|:..::....|
Zfish   130 GHVDFTLEVERALRVLDGAVAVFDASAGVEAQTMTVWRQAEKHQIPCVCFLNKMDKPAASLRYSL 194

  Fly   184 SQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEG----EHGMDIRLDEI-PQD---MRV 240
            ..:::|:..|...:|:|||...:..|:|||:..:.:.::|    ..|....::.: |.|   :.:
Zfish   195 DSIKAKLKANPVLLQIPIGSGKSFTGLVDLITRQKMMWQGNALTNDGRSFEINSLQPSDDPNVLL 259

  Fly   241 ESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKA-----ALRRTCINRTFTPVLVGTALKNK 300
            ...|.|..|||.:::.|:...||.|.|.....|.:.|     |:||..:.|...|||.|::||||
Zfish   260 AVSEARAALIEQVADLDDEFAELLLGEYGENFDAVPAVKLQEAVRRVTLARKGVPVLCGSSLKNK 324

  Fly   301 GVQPLLDAVLDYLPNPGEVENLGFIEKEGQDPEKVVLNPARDGKDPFVGLAFK-LEAGRFGQLTY 364
            ||||||||:..|||.|.|..:                :..|..|:....|||| :...:.|.|.:
Zfish   325 GVQPLLDAITAYLPAPNERNH----------------DLVRWYKNDLCALAFKVVHDKQRGPLVF 373

  Fly   365 LRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGV-DCASGDTFTTN 428
            :|.|.|.::...::.|...|:..:::||:...::|..::..:.||:|....|: ...:|||..::
Zfish   374 VRIYSGSMKAQSSVHNINRNETEKMSRLLLPFADQQIEIPSLSAGNIALTVGLKQTVTGDTIVSS 438

  Fly   429 P-------------------KNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTF 474
            .                   .::.::..:.|||||...:|:|.....:.:...|:....:|||:.
Zfish   439 KASAAAAIRRAQAEAESMSNSHSAALAGVEVPEPVFFCSIEPPTMAKQADLEHALNCLQREDPSL 503

  Fly   475 HFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGG 539
            ....|.|..:|::.||||||:||...|::|||.....||..:||:|||::.......|..:..|.
Zfish   504 KVRIDPDSGQTVLCGMGELHIEIIHDRIKREYKIETHLGPLQVAYRETILQSVTAKDLLDRILGE 568

  Fly   540 SGQYARIIGVMEPLPPNQNTLLEFV-DETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRF 603
            ......:...:.||..|.:...:.. :|.|...:|......||.|.:....:|.:.|..:.|::.
Zfish   569 KRHVVSVELTVHPLKENSSASCDITFEEDVKAMLPADVREAVENGVQSAYLQGPVLGFPVQGVQT 633

  Fly   604 RLQDGGHHIVDSSELAFMLAA---HGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKR 665
            .:||..   ::|...|.|::|   ...:|.:.|.|. |:|||:|.:|||..||...:|:..||:|
Zfish   634 VIQDVR---LESGTSAAMVSACVSRCMLKALKQAGG-QVLEPVMALEVTVGEEHLSSVLADLSQR 694

  Fly   666 HGIITGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQ 724
            .|.|...:..:....:.|:|||.:|.||:..||:.|.|...|::|.|.|.|.  :.|||
Zfish   695 RGTICDIQSRQDNKILLADVPLAEMMGYSTVLRTLTSGNATFSLELSSYEPM--NSQDQ 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	247/725 (34%)
gfm2	NP_001071013.1	FusA	52..760	CDD:440248	247/725 (34%)