Protein Alignment mEFG1 and eIF5B

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_651974.1
• Gene: eIF5B / 44261
• FlyBaseID: FBgn0026259
• Length: 1144
• Species: Drosophila melanogaster
• Alignment Length: 679
• Identity: 138/679 - (20%)
• Similarity: 243/679 - (35%)
• Gaps: 190/679 - (27%)

  Fly    15 RLRALKSLGKAGYSSHAKFSEHKPIERIRN--IGISAHIDSGKTTLTERILFYTGRIAEMH---- 73
            ||||...:.|    ..|:..:.:..:.:|.  :.:..|:|:|||.:.:       ::...|
  Fly   530 RLRAEARILK----RQAEAEKKRSTDELRAGVVCVLGHVDTGKTKILD-------KLRRTHVQDS 583

  Fly    74 EVRG-KDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGA 137
            |..| ...:|||...:|..:::...:::||.:. .:...:.|||||||..|:....|...:.|.|
  Fly   584 EAGGITQQIGATNVPIEAIKEQTKYVKAAAGFE-HRLPGLLIIDTPGHESFSNLRNRGSSLCDIA 647

  Fly   138 VLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRL------------------GSNPYRVLS 184
            :||:..:.|::.||:...:.:|:...|.:..:||:|||                  .||. ::..
  Fly   648 ILVVDIMHGLEPQTIESIQLLKKKKCPFIVALNKIDRLYDWKQLARRDVRDVLKEQQSNT-QLEF 711

  Fly   185 QMRSK--------MNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLDEIPQDMRVE 241
            |.|:|        ...|||...    ..::.|..:.||...||..||...:...:.:..|:|..:
  Fly   712 QQRTKDVILQFAEQGLNAALFY----ENTDPKTYISLVPTSAISGEGMGNLLFMIADFCQNMLAK 772

  Fly   242 SLERRQEL------IEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTALKNK 300
            .|...:||      ::.|.....|:..:.:..|               :....|.|:.||.
  Fly   773 RLMYSEELQATVLEVKALPGLGTTIDAILINGK---------------LREGQTMVVAGTD---- 818

  Fly   301 GVQPLLDAVLDYL-PNPGE---VENLGFIEKEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFGQ 361
              .|::..:...| |.|.:   |:| .::|.:.....:.|...|:|.:....|:.. |.|.:..:
  Fly   819 --GPIVTQIRSLLMPQPMKELRVKN-AYVEYKEVKAAQGVKIAAKDLEKAIAGINL-LIAHKPDE 879

  Fly   362 LTYLRCYQGVLRKGDNIFN----ARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASG 422
            :..  |.:.|.|:..:..:    |:|...|:.:.|                |.:.||.
  Fly   880 VEI--CTEEVARELKSALSHIKLAQTGVHVQASTL----------------GSLEALL------- 919

  Fly   423 DTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLV 487
             .|....|...|...|   .|||...:...:|            ..:.:..:......|||
  Fly   920 -EFLRTSKIPYSAIRI---GPVVKRDVMKAST------------MLEHEAQYATILAFDVK---- 964

  Fly   488 SGMGELHLEIYAQRMEREYGCPVTLG-------------------KPKVAFRETLVGPCEFDYLH 533
                   :|..||.|....|..:...                   |.:..||...|.||:...|
  Fly   965 -------IEREAQEMADSLGVKIFQADIIYHLFDKFTAYREELKQKKREEFRSVAVFPCKLRIL- 1021

  Fly   534 KKQSGGSGQYARIIGVMEPLPPNQNTLLEFVDETVGTNV---PKQF-----VPGVEKGYR--EMA 588
             .|...:.:...::|||.     :|.:::     |||.:   .|:|     |..:|..::  |.|
  Fly  1022 -PQFVFNSRDPIVMGVMV-----ENGIVK-----VGTPICVPSKEFVDIGIVTSIESNHKQIEFA 1075

  Fly   589 EKGM--------LSGH--KLSGIRFRLQD 607
            .||.        :.|.  |:.|..|...|
  Fly  1076 RKGQEICVKIDPIPGESPKMFGRHFEADD 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	132/656 (20%)
eIF5B	NP_651974.1	PRK04004	553..1129	CDD:457675	132/652 (20%)