Protein Alignment mEFG1 and Eef2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_058941.1
• Gene: Eef2 / 29565
• RGDID: 61979
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 856
• Identity: 211/856 - (24%)
• Similarity: 341/856 - (39%)
• Gaps: 187/856 - (21%)

  Fly    42 IRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGAT--MDSMELERQRGITIQSAATY 104
            |||:.:.||:|.||:|||:.::...|.||..       ..|.|  .|:.:.|::|.|||:|.|..
  Rat    19 IRNMSVIAHVDHGKSTLTDSLVCKAGIIASA-------RAGETRFTDTRKDEQERCITIKSTAIS 76

  Fly   105 TLWK----DTN------------INIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLT 153
            ..::    |.|            ||:||:||||||:.||..||||.|||::|:..|.||..||.|
  Rat    77 LFYELSENDLNFIKQSKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTET 141

  Fly   154 VNRQMKRYNVPCLAFINKLDR----LGSNPYRVLSQMRSKMNHNAAFIQLPIGV-ESNCKG--IV 211
            |.||.....:..:..:||:||    |...| ..|.|...::..|...|....|. ||...|  ::
  Rat   142 VLRQAIAERIKPVLMMNKMDRALLELQLEP-EELYQTFQRIVENVNVIISTYGEGESGPMGNIMI 205

  Fly   212 DLVREKAIYFEGEHGMDIRLDEIPQDMRVESLERRQE----LIEHLSNADETLGELFLE------ 266
            |.|.....:..|.||....|.:. .:|.|.....:.|    ..|.....::.:.:|:.:
  Rat   206 DPVLGTVGFGSGLHGWAFTLKQF-AEMYVAKFAAKGEGQLGAAERAKKVEDMMKKLWGDRYFDPA 269

  Fly   267 ----EKPFTEDDIKAALRRTC------INRTFTPVL-----------------VGTALKNKGVQP 304
                .|.....|.|...|..|      |.:.|..::                 :.:..|:|..:|
  Rat   270 NGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKP 334

  Fly   305 LLDAVLD---------------YLPNP--GEVENLGFIEKEGQDPEKVVLNPARDGKDPFVGLAF 352
            ||.||:.               :||:|  .:......:.:...|.|..:...:.|.|.|.:....
  Rat   335 LLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYIS 399

  Fly   353 KL----EAGRFGQLTYLRCYQGVLRKGDNIF----NARTNKK-----VRIARLVRLHSNQMEDVN 404
            |:    :.|||  ..:.|.:.||:..|..:.    |....||     ..|.|.:.:....:|.:.
  Rat   400 KMVPTSDKGRF--YAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIE 462

  Fly   405 EVYAGDIFALFGVD---CASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIAR 466
            :|..|:|..|.|||   ..:|...|....:|:.:.. |...|||.:|::..|..|.....:.:.|
  Rat   463 DVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMK-FSVSPVVRVAVEAKNPADLPKLVEGLKR 526

  Fly   467 FTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGC-PVTLGKPKVAFRETLVGPCEFD 530
            ..|.||......: :..|.:::|.|||||||..:.:|.::.| |:....|.|::|||:.......
  Rat   527 LAKSDPMVQCIIE-ESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVL 590

  Fly   531 YLHKKQSGGSGQYARI---------------IGVMEPLPPNQNTLLE--------------FVDE 566
            .|.|..:..:..|.:.               :...:.|......|.|              |..:
  Rat   591 CLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPD 655

  Fly   567 TVGTNVPKQFVPGVE----------KGYREMAEKGMLSGHKLSGIRFRLQD----------GGHH 611
            ..|.|:......||:          .|::...::|.|....:.|:||.:.|          ||..
  Rat   656 GTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQ 720

  Fly   612 IVDSSE---LAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTE 673
            |:.::.   .|.:|.|..           :::|||.|||:..||:..|.:.|.|:::.|.:....
  Rat   721 IIPTARRCLYASVLTAQP-----------RLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEES 774

  Fly   674 GTEG--WFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPD-----VQDQIVRQYQE 731
            ...|  .|.|.|.:|:|:.||:..:|||:|.|:.        :..|:.|     ..|......:.
  Rat   775 QVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQA--------FPQCVFDHWQILPGDPFDNSSRP 831

  Fly   732 SQGLAQPDKKK 742
            ||.:|:..|:|
  Rat   832 SQVVAETRKRK 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	206/843 (24%)
Eef2	NP_058941.1	PTZ00416	1..858	CDD:240409	211/856 (25%)