Protein Alignment mEFG1 and Gfm1

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_613057.2
• Gene: Gfm1 / 28030
• MGIID: 107339
• Length: 751
• Species: Mus musculus
• Alignment Length: 709
• Identity: 479/709 - (67%)
• Similarity: 580/709 - (81%)
• Gaps: 1/709 - (0%)

  Fly    38 PIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAA 102
            |.|:||||||||||||||||||||:|:||||||.||||:|||.|||.||||||||||||||||||
Mouse    43 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIATMHEVKGKDGVGAVMDSMELERQRGITIQSAA 107

  Fly   103 TYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLA 167
            |||:|||.||||||||||||||:|||||||||||||||||||||||.||:||:|||||||||.|.
Mouse   108 TYTMWKDININIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVSRQMKRYNVPFLT 172

  Fly   168 FINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLD 232
            |||||||:||||.|.|.|||||:||||||:|:|||:|.:.|||:||:.|:||||:|:.|..:|.|
Mouse   173 FINKLDRMGSNPSRALQQMRSKLNHNAAFVQIPIGLEGDFKGIIDLIEERAIYFDGDFGQIVRYD 237

  Fly   233 EIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTAL 297
            |||..:|..:.:.||||||.::|:||.|||||||||..:..|:|.|:||..::|:||||.:|:||
Mouse   238 EIPAGLRAAAADHRQELIECVANSDEQLGELFLEEKIPSVSDLKRAIRRATLSRSFTPVFLGSAL 302

  Fly   298 KNKGVQPLLDAVLDYLPNPGEVENLGFI-EKEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFGQ 361
            |||||||||||||:|||||.||:|...: :.:.::..|:::||.||...||||||||||||||||
Mouse   303 KNKGVQPLLDAVLEYLPNPSEVQNYAILNQNDSKEKTKILMNPQRDDSHPFVGLAFKLEAGRFGQ 367

  Fly   362 LTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFT 426
            |||:|.|||.|:||..|:|.||.||||:.||||:|::.||||.|||||||.||||:|||||||||
Mouse   368 LTYVRNYQGELKKGSTIYNTRTGKKVRVQRLVRMHADMMEDVEEVYAGDICALFGIDCASGDTFT 432

  Fly   427 TNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMG 491
            ....::||||||.|||||:|:|::|:|..|.:.|||.|.|||:|||||...||.:.|||:|||||
Mouse   433 NKDNSDLSMESIHVPEPVISIAMRPSNKNDLEKFSKGIGRFTREDPTFKVHFDPESKETIVSGMG 497

  Fly   492 ELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPPN 556
            ||||||||||||||||||...||||||||||:|.|..||:.|||||||:||:.::|||:|||||.
Mouse   498 ELHLEIYAQRMEREYGCPCITGKPKVAFRETIVAPVPFDFTHKKQSGGAGQFGKVIGVLEPLPPE 562

  Fly   557 QNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFM 621
            ..|.|||.|||.|:||||||||.||||:.:..|||.||||||||:||.||||.||:|||:|::|:
Mouse   563 DYTKLEFSDETFGSNVPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFI 627

  Fly   622 LAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVP 686
            .|..||:|:...||:..|:||||.|||.||.||||.|...:::|||:|||.:|.|.:||:||:||
Mouse   628 RAGEGALKQALANGTLCIIEPIMSVEVIAPNEFQGTVFAGINRRHGVITGQDGIEDYFTLYADVP 692

  Fly   687 LNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQGLAQPDKKKKKN 745
            ||:||||:.||||.|:||||:||||.||.||.|..|::::.:|.|:.|.....|.|.||
Mouse   693 LNNMFGYSTELRSCTEGKGEYTMEYCRYQPCSPSTQEELINKYLEATGQLPVKKGKAKN 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	473/693 (68%)
Gfm1	NP_613057.2	FusA	45..735	CDD:440248	471/689 (68%)