Protein Alignment mEFG1 and mef1

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_595472.2
• Gene: mef1 / 2539776
• PomBaseID: SPBC1306.01C
• Length: 770
• Species: Schizosaccharomyces pombe
• Alignment Length: 765
• Identity: 387/765 - (50%)
• Similarity: 525/765 - (68%)
• Gaps: 50/765 - (6%)

  Fly    13 TLRLRALKSLGKAGYSSHAKF--------------------SEHKPIERIRNIGISAHIDSGKTT 57
            |.||..|.:|...||:|.|..                    ::.|.:::||||||||||||||||
pombe    10 TSRLPRLSTLVVRGYASVANTGIEASNTSENNLNIQEQLNDNDKKRLKQIRNIGISAHIDSGKTT 74

  Fly    58 LTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDT------------ 110
            .|||:|:|||||.::|||||||||||.||.|||||::|||||||||:..|:.|
pombe    75 FTERVLYYTGRIKDIHEVRGKDNVGAKMDFMELEREKGITIQSAATHCTWERTVDQIEANEKQKT 139

  Fly   111 ------NINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFI 169
                  ||||||||||:|||:|||||||||||||||||||.||||||:||:|||:|||||.::|:
pombe   140 DFEKSYNINIIDTPGHIDFTIEVERALRVLDGAVLVLCAVSGVQSQTITVDRQMRRYNVPRISFV 204

  Fly   170 NKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRL-DE 233
            ||:||:|::|::|:.|:.:|:...||.:|:|||.|...:|:|||::.:|||..|..|..|.: .:
pombe   205 NKMDRMGADPWKVIQQINTKLKIPAAAVQIPIGQEDKLEGVVDLIQMRAIYNRGSKGEKIEISQQ 269

  Fly   234 IPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTALK 298
            :|:::...:.|:|..|||.|::.||.:.::::.|:..|.:.:..|:|||.:.|.|||||:|:||.
pombe   270 VPENLIELAKEKRSALIEKLADLDEEIADIYVMEEDPTPEQLMGAIRRTTLARKFTPVLMGSALS 334

  Fly   299 NKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFGQLT 363
            |.|||.:||||.||||||.||||:.....:.:.|  |.|.|:  .:.|.|.||||||.|||||||
pombe   335 NVGVQSVLDAVCDYLPNPSEVENIALNAADSEKP--VSLVPS--SEKPLVALAFKLEEGRFGQLT 395

  Fly   364 YLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFTTN 428
            |||.|||.|::|:.|:|..:.||::::||||:|||.||::.:|.||.|.||||::||||||| |:
pombe   396 YLRIYQGTLKRGNYIYNVNSTKKIKVSRLVRMHSNDMEEIEKVEAGGICALFGIECASGDTF-TD 459

  Fly   429 PKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGEL 493
            ...:.:|.|:||||||:|:::|| .:||..:||||:.||.:|||||....||:.|||::||||||
pombe   460 GSVSYTMTSMFVPEPVISLSLKP-KSKDTTSFSKALNRFQREDPTFRVQLDNESKETIISGMGEL 523

  Fly   494 HLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPL----P 554
            |||:|.:||.|||......|||:|||||||.....|.|||||||||:||||::.|.:|.:    .
pombe   524 HLEVYVERMRREYKVDCETGKPRVAFRETLSKKVPFSYLHKKQSGGAGQYAKVEGYIEYMDGVED 588

  Fly   555 PNQNTL-LEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSEL 618
            .:.|.: .||:::..|..||.|::|..||.:.|..:||.|.||.:...||.|:||.:|.||||||
pombe   589 ESGNVVDCEFINKVTGGTVPTQYIPACEKAFYEALKKGFLIGHPIKNCRFVLEDGAYHPVDSSEL 653

  Fly   619 AFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYA 683
            ||.||...|.:..|...:..:|||||.|.:|||.|.||.|:|:|.||...|..::..|..||:.|
pombe   654 AFRLATISAFRTAFLQANPMVLEPIMNVSITAPVEHQGGVIGNLDKRKATIVDSDTDEDEFTLQA 718

  Fly   684 EVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQ 733
            |||||.||.|:.::|:.|:|||||:||:.:|.|....||.::|..|.:.|
pombe   719 EVPLNSMFSYSSDIRALTKGKGEFSMEFLKYLPAPKYVQKELVDAYNKQQ 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	376/716 (53%)
mef1	NP_595472.2	FusA	53..768	CDD:440248	377/720 (52%)