Protein Alignment mEFG1 and Y119D3B.14

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_497345.2
• Gene: Y119D3B.14 / 191043
• WormBaseID: WBGene00022491
• Length: 731
• Species: Caenorhabditis elegans
• Alignment Length: 772
• Identity: 227/772 - (29%)
• Similarity: 369/772 - (47%)
• Gaps: 106/772 - (13%)

  Fly    16 LRALKSLGKAGYSSHAKFSEHKPI-ERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKD 79
            ||.|..|.:..||:    ....|. .::||||:.||:|:||||:|||:|:..|.|    .|.|..
 Worm     2 LRLLLLLSRRCYST----PPPPPAPSKLRNIGVIAHVDAGKTTVTERLLYLAGAI----HVAGHV 58

  Fly    80 NVGATM-DSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCA 143
            :.|.|: |.:::||:||||:||||....||...||:|||||||||.|||||.:|||||.|:|:..
 Worm    59 DKGNTVTDFLDIERERGITVQSAAVNLDWKGHRINLIDTPGHVDFRVEVERCVRVLDGIVVVIDG 123

  Fly   144 VGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNC- 207
            ..|||.|||||.||..::.:|...||||:|:|.:|....:..:..|:...|..:.:|:......
 Worm   124 SAGVQPQTLTVWRQSSKFKLPAHFFINKMDKLAANFENSVDSVEQKLGVRAVKLVVPLPENRGFN 188

  Fly   208 KGIVDLVREKAIYFEGEHGMDIRLDEIPQDMRVESL--ERRQELIEHLSNADETLGELFLEEKPF 270
            :|.:|::..|.:     .|........|::.....|  |.:.||...|:::.......||:|...
 Worm   189 RGFLDILHSKML-----PGNSKNWQNPPKNSPEAELLAEHKSELCFTLADSHADFQSKFLDEFDG 248

  Fly   271 TED-----DIKAALRR-TCINRTFTPVLVGTALKN-KGVQPLLDAVLDYLPNPGEVENLGFIEKE 328
            ..:     ::|:.||. ||.::..| :..|:|:|| ..|:|:||||:|:.|.| |:.|..|.:..
 Worm   249 NSEKIDVIEMKSVLRELTCASKIAT-ISCGSAVKNVHCVKPVLDAVVDFFPAP-EMRNREFRDVF 311

  Fly   329 GQDPEKVVLNPARDGKDPFVGLAFKL-EAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARL 392
            |:|               ..||.||: ...|.|||:|:|.|.|.|.....|||..........:|
 Worm   312 GED---------------LSGLVFKITHDKRRGQLSYMRIYTGSLHNNSTIFNTSQMTSEGPLKL 361

  Fly   393 VRLHSNQMEDVNEVYAGDIFALFGVD-CASGDTFTT--------------------NPK--NNLS 434
            ...:::::..|.:|.||:|..:.|:. ..:|||...                    :||  |::.
 Worm   362 FTPYADELRLVEQVSAGNITVVAGLQTTVTGDTVVASSASAEKACQKLAGSESSLLSPKDGNSVV 426

  Fly   435 MESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYA 499
            ...|..|:.|....|:|.:.:..:.|:||:...|:|||:....||.|..:|:|...||||||...
 Worm   427 FSGIESPDAVFFCCIEPPSNRQLNQFNKALEELTREDPSMKIRFDRDTGQTIVETQGELHLEAIK 491

  Fly   500 QRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGS----GQYARIIGVMEPLPPNQNTL 560
            .|::|.|...|.:||.:||:||.|..  |..|..|.:.|.|    .::.::...:||      |.
 Worm   492 DRLKRNYKLDVFIGKLQVAYREMLTE--ELSYTAKVEDGLSEKKRPEFVQLTMRLEP------TQ 548

  Fly   561 LEFVDETVGTNVPKQFVP-------GVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSEL 618
            .....:.:...:|:...|       .|.:|.....:.|.|:.:.:..:|..|.:   .||...::
 Worm   549 AHIPFKKIELELPQTARPVRLDWQKAVNEGCSNALQNGPLASYPVHAVRVVLTE---CIVSGGKI 610

  Fly   619 --AFMLA-AHGAIKEVFQNGSWQILEPIMLVEV-------TAPEEFQGAVMGHLSKRHGIITGTE 673
              |.:.| |...:.|...:|...:.||:|.|::       |.|      ::..|.:|......::
 Worm   611 NPALLSACAQKCVSEALSSGEMVLTEPVMEVQIEIRNDDPTQP------ILNELLRRRAHFEHSD 669

  Fly   674 GTEGW--FTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQ 728
            .||..  ..:.|.:||::....:..:|:.|.|.|:.::::..|.......:.:|:::
 Worm   670 ATESTEIRRICAILPLSETENLSKTVRTLTSGFGDISVQFRGYQQVTEHEKMEILKK 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	221/750 (29%)
Y119D3B.14	NP_497345.2	FusA	23..728	CDD:440248	220/747 (29%)