Protein Alignment mEFG1 and Gfm1

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_446077.2
• Gene: Gfm1 / 114017
• RGDID: 631396
• Length: 751
• Species: Rattus norvegicus
• Alignment Length: 709
• Identity: 478/709 - (67%)
• Similarity: 580/709 - (81%)
• Gaps: 1/709 - (0%)

  Fly    38 PIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAA 102
            |.|:||||||||||||||||||||:|:||||||.||||:|||.|||.||||||||||||||||||
  Rat    43 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIATMHEVKGKDGVGAVMDSMELERQRGITIQSAA 107

  Fly   103 TYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLA 167
            |||:|:|.||||||||||||||:|||||||||||||||||||||||.||:||:|||||||||.|.
  Rat   108 TYTMWRDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVSRQMKRYNVPFLT 172

  Fly   168 FINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLD 232
            |||||||:||||.|.|.|||||:||||||:|:|||:|.:.|||:||:.|:||||:|:.|..:|.|
  Rat   173 FINKLDRMGSNPARALQQMRSKLNHNAAFVQIPIGLEGDFKGIIDLIEERAIYFDGDFGQIVRYD 237

  Fly   233 EIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTAL 297
            |||.|:|..:.:.||||||.::|:||.|||||||||..:..|:|.|:||..::|:||||.:|:||
  Rat   238 EIPADLRAAAADHRQELIECVANSDEQLGELFLEEKIPSVSDLKLAIRRATLSRSFTPVFLGSAL 302

  Fly   298 KNKGVQPLLDAVLDYLPNPGEVENLGFI-EKEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFGQ 361
            |||||||||||||::||||.||:|...: :.:.::..|:::||.||...||||||||||||||||
  Rat   303 KNKGVQPLLDAVLEFLPNPSEVQNYALLNQNDSKEKNKILMNPKRDDSHPFVGLAFKLEAGRFGQ 367

  Fly   362 LTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFT 426
            |||:|.|||.|:||..|:|.||.||||:.||||:|::.||||.|||||||.||||:|||||||||
  Rat   368 LTYVRNYQGELKKGSTIYNTRTGKKVRVQRLVRMHADMMEDVEEVYAGDICALFGIDCASGDTFT 432

  Fly   427 TNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMG 491
            ....::||||||.||:||:|:|:||:|..|.:.|||.|||||:|||||...||.:.|||:|||||
  Rat   433 NKDNSDLSMESIHVPDPVISVAMKPSNKNDLEKFSKGIARFTREDPTFKVHFDTESKETIVSGMG 497

  Fly   492 ELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPPN 556
            ||||||||||||||||||...||||||||||:..|..||:.|||||||:|||.::|||:|||.|.
  Rat   498 ELHLEIYAQRMEREYGCPCITGKPKVAFRETVTAPVPFDFTHKKQSGGAGQYGKVIGVLEPLAPE 562

  Fly   557 QNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFM 621
            ..|.|||.|||.|.||||||||.||||:.:..|||.||||||||:||.||||.||:|||:|::|:
  Rat   563 DYTKLEFSDETFGANVPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFI 627

  Fly   622 LAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVP 686
            .|..||:|:...:.:..|:||||.|||.||.||||||...:::|||:|||.:|.|.:||:||:||
  Rat   628 RAGEGALKQALASATLCIIEPIMSVEVIAPNEFQGAVFAGINRRHGVITGQDGIEDYFTLYADVP 692

  Fly   687 LNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQGLAQPDKKKKKN 745
            ||:||||:.||||.|:||||:||||:||.||.|..|:::|.:|.|:.|.....|.|.||
  Rat   693 LNNMFGYSTELRSCTEGKGEYTMEYNRYQPCSPSTQEELVNKYLEATGQLPVKKGKAKN 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	472/693 (68%)
Gfm1	NP_446077.2	FusA	45..735	CDD:440248	470/689 (68%)