Protein Alignment mEFG1 and gfm2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_004910454.1
• Gene: gfm2 / 100492326
• XenbaseID: XB-GENE-1002407
• Length: 777
• Species: Xenopus tropicalis
• Alignment Length: 741
• Identity: 241/741 - (32%)
• Similarity: 371/741 - (50%)
• Gaps: 90/741 - (12%)

  Fly    38 PIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAA 102
            |:.:||||||.||||:||||.|||:|:|:|.|..:.:|...|.|   .|.|..||:|||||||||
 Frog    63 PVSKIRNIGIMAHIDAGKTTTTERMLYYSGYIRALGDVDDGDTV---TDYMAQERERGITIQSAA 124

  Fly   103 TYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLA 167
            ....|....||:|||||||||||||||:||||||||.|..|..||::|||||.||..|:.:|.|.
 Frog   125 VTFDWNGHRINLIDTPGHVDFTVEVERSLRVLDGAVAVFDASAGVEAQTLTVWRQADRHTIPRLC 189

  Fly   168 FINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYF-------EGEH 225
            ||||:|:.|::....:..::.|:......:|||:|...:.||:||||..:.|.:       :|.|
 Frog   190 FINKMDKTGASFNYAVESIKEKLKVKPLVLQLPVGEGKSFKGLVDLVSMETILWNPRAQEDDGRH 254

  Fly   226 GMDIRLDEIPQDMRVESL--ERRQELIEHLSNADETLGELFLEEKPFTE-------DDIKAALRR 281
            .....:.|| .|:.:..:  :.|..|||.:::.|:....|.|.|  :::       :.::.|:||
 Frog   255 FEKKAVKEI-SDVEILDIATDGRNALIEQVADLDDEFAALILGE--YSDHFDLVPLEKLQMAIRR 316

  Fly   282 TCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQDPEKVVLNPARDGKDP 346
            ..:.:...|:|.|:|||||||||||||:..|||:|.:..: .|::....|
 Frog   317 ITLAQLAVPILCGSALKNKGVQPLLDAITLYLPSPEDFSH-DFVKWYQGD--------------- 365

  Fly   347 FVGLAFK-LEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGD 410
            ...|||| :...:.|.:.::|.|.|.::....::|...|...|::||:...::|..::..:.:|:
 Frog   366 LCALAFKVMHDKQRGPMVFVRIYSGNMKPQSALYNVNQNCTERMSRLLLPFADQHVEIPSLSSGN 430

  Fly   411 IFALFGV-DCASGDTFTTN-----------------------PKNNLSMESIFVPEPVVSMAIKP 451
            |....|: ..|:|||..::                       .:.:|.:..:.:||||....|:|
 Frog   431 IALTVGLKQAATGDTIVSSKAAAAAAARRAGREGDKKHRDGKTEGSLVLAGVEIPEPVFFCTIEP 495

  Fly   452 NNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPK 516
            .:...:.:...|:....:|||:.....|.|..:.::.||||||:||..:|:.:|||....||..:
 Frog   496 PSAARQPDLENALRCLQREDPSLKVKVDADSGQMILCGMGELHIEIIHERIRQEYGLETYLGPLQ 560

  Fly   517 VAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPP-------------NQNTLLEFVDETV 568
            :|:|||::          ..|..|....|.:|.|..|..             ..|.::|:..| :
 Frog   561 IAYRETIL----------SASSASDTLDRTVGDMRHLVTVELEVKPCATDGHGPNPVIEYAKE-I 614

  Fly   569 GTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFMLAAHGAIKEVFQ 633
            ...:.|.|...||.|......:|.|.|..|..:...:.....|...|..:.....:. .:.:..:
 Frog   615 SEPLLKDFQEAVENGISSSYLQGPLLGSPLQDVGVTVNSVSVHPGTSVTMVSACVSR-CMSKALK 678

  Fly   634 NGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVPLNDMFGYAGELR 698
            ....|:|||:|.:|:|..||.....:|.|::|.|.|...........|.|.|||.:|.||:.:||
 Frog   679 KAEKQVLEPLMKLEITVSEEHLSCALGDLAQRRGNIQEILSRSDNKVVVAYVPLAEMMGYSTDLR 743

  Fly   699 SSTQGKGEFTMEYSRYSPCLPDVQDQ 724
            |.|.|...||:|.|.|...  ::|||
 Frog   744 SLTSGSATFTLELSNYEAM--NMQDQ 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	241/741 (33%)
gfm2	XP_004910454.1	FusA	63..775	CDD:440248	241/741 (33%)