Protein Alignment MICU1 and CG4704

DIOPT Version :10

• Sequence 1: NP_001097110.1
• Gene: MICU1 / 33999
• FlyBaseID: FBgn0031893
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_651103.1
• Gene: CG4704 / 42706
• FlyBaseID: FBgn0039029
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 356
• Identity: 135/356 - (37%)
• Similarity: 211/356 - (59%)
• Gaps: 28/356 - (7%)

  Fly   164 IEYENRIRQFSTPDKVFRYFATIQVPVADDRHEVYMTPTDFLTSMTPGMKQPDGLGLDQYRRYDP 228
            ::||||:|..:.|.|:|||||||::.....:.|:||||.|||.|:.||:|||:.||||:::..|.
  Fly     1 MQYENRLRLHAHPTKIFRYFATIKMKNKSGKWELYMTPNDFLRSIQPGLKQPENLGLDKFQILDE 65

  Fly   229 KSVGEQLNLHLEKNSIFYKLGSYGLITFSDYIFLLTVLSISRRHFEIAFRMFDLNGDGDVDCEEF 293
            .:..:.:. .::.:|||.|:...||:|:|||:.|..:|||..|:..|:|::|||||||||..:|.
  Fly    66 HAANKWIP-EVKDDSIFLKIEKRGLLTYSDYVLLTILLSIPERNVRISFKLFDLNGDGDVTIDEL 129

  Fly   294 EMVATLVRQ-QTSMGTRHRDHANTGNTFKGVNSALITYFFGPNMDEKLTIEKFLDFQEQLQREIL 357
            :.|...:.| :.||                :||.|.::|||..:::.|:|::||.|...|..||.
  Fly   130 DTVFMAMTQGEVSM----------------MNSHLKSHFFGHRLNKTLSIDEFLKFLHALHIEIH 178

  Fly   358 SLEFERKEPNDEGNITEADFAELLLAYAGYPLKKKQKK----LKRVKRRFRDHGKGISKQDYLDF 418
            :.:|:.........|:|.|||:::|.     |:|.:.:    |||||::|.....||:.:::|.|
  Fly   179 TDQFQNLLKESSSVISELDFAKVVLG-----LRKSRSERREILKRVKKKFGQMDHGITLEEFLAF 238

  Fly   419 FHFLNNINDVDTALTFYHIAGASIDQQTLQHVAKTVAMVNLSDHVVDVVFTIFDENNDNQLSNKE 483
            |.|:.:::.:|.||.||:..||.|..:|::|:|..|..|.||.|:.||:|.|||.||||.:..||
  Fly   239 FRFVQDVSIMDNALAFYYFTGADISPKTMRHIAYVVTGVKLSQHLTDVIFCIFDRNNDNIIQRKE 303

  Fly   484 FISVMKNRVQRGLEKPKDTGFLKMMRSVFKC 514
            |.. |:.:....:...|:...|..|..|.||
  Fly   304 FTD-MRRQWMHPIPLRKNPKLLSKMCIVCKC 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU1	NP_001097110.1	EFh_MICU	272..492	CDD:320080	81/224 (36%)
		EF-hand motif	272..301	CDD:320080	13/28 (46%)
		EF-hand motif	326..425	CDD:320080	33/102 (32%)
		EF-hand motif	426..455	CDD:320080	11/28 (39%)
		EF-hand motif	463..492	CDD:320080	14/28 (50%)
CG4704	NP_651103.1	EFh_MICU	108..312	CDD:320080	81/225 (36%)
		EF-hand motif	108..137	CDD:320080	13/28 (46%)
		EF-hand motif	147..177	CDD:320080	10/29 (34%)
		EF-hand motif	178..275	CDD:320080	32/101 (32%)
		EF-hand motif	283..312	CDD:320080	14/29 (48%)