Protein Alignment MICU1 and micu1

DIOPT Version :10

• Sequence 1: NP_001097110.1
• Gene: MICU1 / 33999
• FlyBaseID: FBgn0031893
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_012809601.1
• Gene: micu1 / 100127574
• XenbaseID: XB-GENE-953464
• Length: 479
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 230/427 - (53%)
• Similarity: 314/427 - (73%)
• Gaps: 16/427 - (3%)

  Fly   102 MLTPKVDADAGQRPSSAADVNGEDKSSESESEDSEDE-EAGSDLHLHEGKKIREKVGFRERKIIE 165
            :|..:.:|:|    .|:...:..:::||.|.||::.. |:..:....||||.:.:||||:||::|
 Frog    50 LLWKRANAEA----QSSVKHSMREETSEKEKEDADQAVESSDEDQPQEGKKKKARVGFRDRKVME 110

  Fly   166 YENRIRQFSTPDKVFRYFATIQVPVADDRHEVYMTPTDFLTSMTPGMKQPDGLGLDQY--RRYDP 228
            ||||||.:|||||:||||||::|.......||:|||.||:.|:||..|||:.|||||:  :|||.
 Frog   111 YENRIRAYSTPDKIFRYFATLKVIHESGESEVFMTPQDFVRSITPNEKQPENLGLDQFIIKRYDG 175

  Fly   229 K------SVGEQLNLHLEKNSIFYKLGSYGLITFSDYIFLLTVLSISRRHFEIAFRMFDLNGDGD 287
            |      .:.::.....:::||||.||..|||:|||||||.||||..:|:|||||:||||||||:
 Frog   176 KDFWQTEKISQEREKFADEDSIFYSLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGE 240

  Fly   288 VDCEEFEMVATLVRQQTSMGTRHRDHANTGNTFK-GVNSALITYFFGPNMDEKLTIEKFLDFQEQ 351
            ||.||||.|.:::|.|||||.||||.:.||||.| |.:|||.|||||.::..||||:.||:||.:
 Frog   241 VDMEEFEQVQSIIRSQTSMGMRHRDRSTTGNTLKTGFSSALTTYFFGADLKGKLTIKNFLEFQRK 305

  Fly   352 LQREILSLEFERKEPNDEGNITEADFAELLLAYAGYPLKKKQKKLKRVKRRFRDHGKGISKQDYL 416
            ||.::|.|||||.:|.| |:|||..|..:||||:|...||....||::|:||:| .:|::.::..
 Frog   306 LQHDVLKLEFERHDPVD-GHITERQFGSMLLAYSGVQSKKLTHMLKQLKKRFKD-AEGLTFEEVE 368

  Fly   417 DFFHFLNNINDVDTALTFYHIAGASIDQQTLQHVAKTVAMVNLSDHVVDVVFTIFDENNDNQLSN 481
            :||.||.|||||||||:|||:||||:|:.|:|.||:|||.|.|||||.||||.:||.:.:.:|||
 Frog   369 NFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSN 433

  Fly   482 KEFISVMKNRVQRGLEKPKDTGFLKMMRSVFKCAKET 518
            ||||::||.|:.||||||||.||.::||:::|||:||
 Frog   434 KEFIAIMKQRLMRGLEKPKDMGFTRLMRAMWKCAQET 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU1	NP_001097110.1	EFh_MICU	272..492	CDD:320080	130/220 (59%)
		EF-hand motif	272..301	CDD:320080	20/28 (71%)
		EF-hand motif	326..425	CDD:320080	48/98 (49%)
		EF-hand motif	426..455	CDD:320080	20/28 (71%)
		EF-hand motif	463..492	CDD:320080	16/28 (57%)
micu1	XP_012809601.1	EFh_MICU1	225..444	CDD:320081	130/220 (59%)
		EF-hand motif	225..254	CDD:320081	20/28 (71%)
		EF-hand motif	280..310	CDD:320081	17/29 (59%)
		EF-hand motif	378..407	CDD:320081	20/28 (71%)
		EF-hand motif	415..444	CDD:320081	16/28 (57%)