Protein Alignment Rab30 and RAB37

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_001006639.1
• Gene: RAB37 / 326624
• HGNCID: 30268
• Length: 223
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 90/209 - (43%)
• Similarity: 127/209 - (60%)
• Gaps: 17/209 - (8%)

  Fly     4 YKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQG-ATIGVDFMIKTVEVEGEKIKLQIWDTAGQE 67
            |....|::|:|:.||||||.:.:|..|.|..|.. ||:|:||..|.|.|:|.::|||||||||||
Human    26 YDLTGKVMLLGDTGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQE 90

  Fly    68 RFRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTD-RDDREIPT 131
            ||||:|.:|||.|.||:|:|||:.:.:||.:..||.||.|||...|:.:|:|||.| ..:|.|.:
Human    91 RFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADMSSERVIRS 155

  Fly   132 QIGEEFAKQHDMYFLETSAKEAENVERLFYEIAAELIGQARSKDGSSSAAAAAAQRQSEGSSIGL 196
            :.||..|:::.:.|||||||...|||..|..||.||              ...|..|::..|..:
Human   156 EDGETLAREYGVPFLETSAKTGMNVELAFLAIAKEL--------------KYRAGHQADEPSFQI 206

  Fly   197 GSF-SAKAAQSNCC 209
            ..: .::..:|:||
Human   207 RDYVESQKKRSSCC 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	83/165 (50%)
RAB37	NP_001006639.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		Rab26	31..220	CDD:206695	87/202 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	52..67		6/14 (43%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	85..102		13/16 (81%)