Protein Alignment Hmgcl and LEU4

DIOPT Version :9

• Sequence 1: NP_001285696.1
• Gene: Hmgcl / 33978
• FlyBaseID: FBgn0031877
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_014295.1
• Gene: LEU4 / 855619
• SGDID: S000005048
• Length: 619
• Species: Saccharomyces cerevisiae
• Alignment Length: 305
• Identity: 57/305 - (18%)
• Similarity: 98/305 - (32%)
• Gaps: 78/305 - (25%)

  Fly    34 RDGLQNEPKLLPAATKIELINQLSETGLRTIEA-------TSF-------------VSAKWVPQM 78
            |||.|:.|..:....|.|..::|...|.:.||.       |.|             ||.:.:.|.
Yeast    69 RDGNQSLPDPMSVEQKKEYFHKLVNIGFKEIEVSFPSASQTDFDFTRYAVENAPDDVSIQCLVQS 133

  Fly    79 GDN-----AEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAE 138
            .::     .|.|.|.:|.|                        :..:.|.||.|.....|.:..|
Yeast   134 REHLIKRTVEALTGAKKAT------------------------IHTYLATSDMFREIVFNMSREE 174

  Fly   139 AIERFKPVLKAAQK--------------HGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMG 189
            ||.:.....|..:|              :......:..|    |.|.||.....||......:..
Yeast   175 AISKAVEATKLVRKLTKDDPSQQATRWSYEFSPECFSDT----PGEFAVEICEAVKKAWEPTEEN 235

  Fly   190 CYEISLGDTIGVGTPGTMRRMLDEVTKVVPAKD---LAVHCHDTYGQALSNILVSLDYGIRVVDS 251
            ....:|..|:.|.:|......::.....:..::   ::.|||:..|..::...:.:..|...|:
Yeast   236 PIIFNLPATVEVASPNVYADQIEYFATHITEREKVCISTHCHNDRGCGVAATELGMLAGADRVE- 299

  Fly   252 SVSGLGGCPYAKG-ASGNAATEDVVYLLHGMGLDTGVNLDKLIQV 295
                  ||.:..| .:||.....|...::..|:...::...|..|
Yeast   300 ------GCLFGNGERTGNVDLVTVAMNMYTQGVSPNLDFSDLTSV 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmgcl	NP_001285696.1	HMGL-like	25..299	CDD:279072	57/305 (19%)
		DRE_TIM_HMGL	28..300	CDD:163676	57/305 (19%)
LEU4	NP_014295.1	leuA_yeast	35..596	CDD:273371	57/305 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343033
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740