Protein Alignment Hmgcl and LEU4

DIOPT Version :10

• Sequence 1: NP_609089.1
• Gene: Hmgcl / 33978
• FlyBaseID: FBgn0031877
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_014295.1
• Gene: LEU4 / 855619
• SGDID: S000005048
• Length: 619
• Species: Saccharomyces cerevisiae
• Alignment Length: 301
• Identity: 58/301 - (19%)
• Similarity: 97/301 - (32%)
• Gaps: 70/301 - (23%)

  Fly    34 RDGLQNEPKLLPAATKIELINQLSETGLRTIEA-------TSF-------------VSAKWVPQM 78
            |||.|:.|..:....|.|..::|...|.:.||.       |.|             ||.:.:.|.
Yeast    69 RDGNQSLPDPMSVEQKKEYFHKLVNIGFKEIEVSFPSASQTDFDFTRYAVENAPDDVSIQCLVQS 133

  Fly    79 GDN-----AEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAE 138
            .::     .|.|.|.:|.|                        :..:.|.||.|.....|.:..|
Yeast   134 REHLIKRTVEALTGAKKAT------------------------IHTYLATSDMFREIVFNMSREE 174

  Fly   139 AIERFKPVLKAAQK------HGVRVRGYVSTVVGC----PYEGAVAPSAVVKVVEALYQMGCYEI 193
            ||.:.....|..:|      .....|........|    |.|.||.....||......:......
Yeast   175 AISKAVEATKLVRKLTKDDPSQQATRWSYEFSPECFSDTPGEFAVEICEAVKKAWEPTEENPIIF 239

  Fly   194 SLGDTIGVGTPGTMRRMLDEVTKVVPAKD---LAVHCHDTYGQALSNILVSLDYGIRVVDSSVSG 255
            :|..|:.|.:|......::.....:..::   ::.|||:..|..::...:.:..|...|:
Yeast   240 NLPATVEVASPNVYADQIEYFATHITEREKVCISTHCHNDRGCGVAATELGMLAGADRVE----- 299

  Fly   256 LGGCPYAKG-ASGNAATEDVVYLLHGMGLDTGVNLDKLIQV 295
              ||.:..| .:||.....|...::..|:...::...|..|
Yeast   300 --GCLFGNGERTGNVDLVTVAMNMYTQGVSPNLDFSDLTSV 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmgcl	NP_609089.1	DRE_TIM_HMGL	28..300	CDD:163676	58/301 (19%)
LEU4	NP_014295.1	leuA_yeast	35..596	CDD:273371	58/301 (19%)