Protein Alignment Hmgcl and LEU9

DIOPT Version :8

• Sequence 1: NP_001285696.1
• Gene: Hmgcl / 33978
• FlyBaseID: FBgn0031877
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_014751.1
• Gene: LEU9 / 854275
• SGDID: S000005634
• Length: 604
• Species: Saccharomyces cerevisiae
• Alignment Length: 291
• Identity: 59/292 (20%)
• Similarity: 106/292 (36%)
• Gaps: 32/292 (11%)

  Fly    34 RDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAK-----WVPQMGDNAEVLKGIRKVTG 93
            |||.|:.|..:..|.|.|..::|...|.:.|| .||.||.     :.....:||....||:.:..
Yeast    68 RDGNQSLPDPMSVAQKKEYFHKLINIGFKEIE-VSFPSASQTDFDFTRYAVENAPDDVGIQCLVQ 131

  Fly    94 ISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQK------ 152
            ....::...::....|..|   .:..:.|.||.|.....|.:..|||.:.....|..:|
Yeast   132 SREHLIKRTVEALTGAKRA---TIHTYLATSDMFREIVFNMSREEAISKAVEATKLVRKLTKDDP 193

  Fly   153 HGVRVRGYVSTVVGC----PYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDE 213
            .....|........|    |.|.||.....||......:......:|..|:.|.:|......::.
Yeast   194 SQQATRWSYEFSPECFSDTPGEFAVEICEAVKKAWEPTEENPIIFNLPATVEVASPNVYADQIEY 258

  Fly   214 VTKVVPAKD---LAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLGGCPYAKG-ASGNAATEDV 274
            .:..:..::   ::.|||:..|..::...:.:..|...|:       ||.:..| .:||.....|
Yeast   259 FSTHITEREKVCISTHCHNDRGCGVAATELGMLAGADRVE-------GCLFGNGERTGNVDLVTV 316

  Fly   275 VYLLHGMGLDTGVNLDKLIQVGRYI--CTEL 303
            ...::..|:...::...|..:...:  |.::
Yeast   317 AMNMYTQGVSPNLDFSDLTSISEIVHRCNKI 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmgcl	NP_001285696.1	HMGL-like	25..299	CDD:279072	58/284 (20%)
		DRE_TIM_HMGL	28..300	CDD:163676	58/287 (20%)
LEU9	NP_014751.1	leuA_yeast	34..596	CDD:273371	59/292 (20%)
		DRE_TIM_LeuA	59..343	CDD:163680	58/286 (20%)
		LeuA_dimer	455..594	CDD:214910

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C116622
eggNOG	1	0.900				E1_COG0119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830