Protein Alignment Hmgcl and LEU9

DIOPT Version :10

• Sequence 1: NP_609089.1
• Gene: Hmgcl / 33978
• FlyBaseID: FBgn0031877
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_014751.1
• Gene: LEU9 / 854275
• SGDID: S000005634
• Length: 604
• Species: Saccharomyces cerevisiae
• Alignment Length: 295
• Identity: 58/295 - (19%)
• Similarity: 107/295 - (36%)
• Gaps: 40/295 - (13%)

  Fly    34 RDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAK-----WVPQMGDNAEVLKGIRKVTG 93
            |||.|:.|..:..|.|.|..::|...|.:.|| .||.||.     :.....:||....||:.:..
Yeast    68 RDGNQSLPDPMSVAQKKEYFHKLINIGFKEIE-VSFPSASQTDFDFTRYAVENAPDDVGIQCLVQ 131

  Fly    94 ISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQK------ 152
            ....::...::....|..|   .:..:.|.||.|.....|.:..|||.:.....|..:|
Yeast   132 SREHLIKRTVEALTGAKRA---TIHTYLATSDMFREIVFNMSREEAISKAVEATKLVRKLTKDDP 193

  Fly   153 --------HGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRR 209
                    :......:..|    |.|.||.....||......:......:|..|:.|.:|.....
Yeast   194 SQQATRWSYEFSPECFSDT----PGEFAVEICEAVKKAWEPTEENPIIFNLPATVEVASPNVYAD 254

  Fly   210 MLDEVTKVVPAKD---LAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLGGCPYAKG-ASGNAA 270
            .::..:..:..::   ::.|||:..|..::...:.:..|...|:       ||.:..| .:||..
Yeast   255 QIEYFSTHITEREKVCISTHCHNDRGCGVAATELGMLAGADRVE-------GCLFGNGERTGNVD 312

  Fly   271 TEDVVYLLHGMGLDTGVNLDKLIQVGRYI--CTEL 303
            ...|...::..|:...::...|..:...:  |.::
Yeast   313 LVTVAMNMYTQGVSPNLDFSDLTSISEIVHRCNKI 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmgcl	NP_609089.1	DRE_TIM_HMGL	28..300	CDD:163676	57/290 (20%)
LEU9	NP_014751.1	leuA_yeast	34..596	CDD:273371	58/295 (20%)