DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13775 and si:dkeyp-117b8.4

DIOPT Version :9

Sequence 1:	NP_001285694.1	Gene:	CG13775 / 33975	FlyBaseID:	FBgn0031874	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_005165631.1	Gene:	si:dkeyp-117b8.4 / 101884515	ZFINID:	ZDB-GENE-060526-362	Length:	974	Species:	Danio rerio

Alignment Length:	827	Identity:	163/827 - (19%)
Similarity:	283/827 - (34%)	Gaps:	239/827 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KKKSNVWQYFYKTSGTVATCLLCNRNYSRRGRGTTCLRNHLKSKH-------PP----------- 49
            ::.|.||.::.:.|.....|..|.|..|.. ..||.:|.||..||       ||
Zfish   117 RRTSKVWNHYTQLSLHRVECNHCKRQLSFH-NSTTSMREHLGRKHSIREGVVPPHNTAGIPTPGA 180

  Fly    50 -----------EFLSLSGDIKYLDL----VKSE------ISIG-------------SPQHPTAQL 80
                       ...:.:|::.:..|    ||.|      ..:|             :|...|:..
Zfish   181 LHSHIQSTLHGNRCNNTGNVTFQPLLPVTVKEEHEEILPAEMGEAKAARTSYAPDCAPGSSTSGS 245

  Fly    81 ELNLHETDSD-----------PLDTEDISYSKRCD---------EKLALMLLNHSF------EFI 119
            ....|: |:|           .:.:.....|.||.         |.|..::|...|      ..:
Zfish   246 NAITHQ-DTDMGCLMYNFPAGEMSSTAGGSSSRCGTRACSNKRAEVLTDLILEMVFRDLQPLSVV 309

  Fly   120 EGPGFVNFIRTLQPRYTIQPRSYYEKILCED---IQRKMHQHLKQQVDLLD-AISLSTSLWR--- 177
            |..||...:..|:|.|.:...|....:|...   :::.:.|||  |..|.. .::|.|..||
Zfish   310 EERGFKLLLSCLEPNYPVPSPSLLGSLLWHRYHVLKQCLQQHL--QTSLASHYMTLCTEYWRSVE 372

  Fly   178 ----GDKGEGLLSLSCSGISRDFQTHRLMLKCE---ALNYESTSKLACCIRDLVPSLAIE--VPK 233
                |..|:..||:|...|...::..|.||:..   .|....:.:......|.:.::..|  :.:
Zfish   373 GCGVGGDGQYYLSVSAHFIDSQWRLARCMLETRPIAELKGNPSERGQVSFADTLKAVLSEFQLSE 437

  Fly   234 EKIHCVIRDEMT--------------ALPG-------SLPD------CSVHRLQMCVRFALQSNE 271
            ..:.||:.|..:              ..||       .||.      |:...|::||:..|....
Zfish   438 NSVFCVMHDTPSDSESRQSIDREFPQEFPGPSHPPPRKLPKGWAPLLCAGQALKLCVQEGLCVES 502

  Fly   272 LLQNLSSKCKQIVDHFASSKMANDHLKFIQEIRLTRDPCTLTPYDPCQWNSAFQMMSSVFRMKDA 336
            :.|.|:. .:.||.||..:..|:..|....| .:.::..:|...||.:|.:|..|..|:..:|..
Zfish   503 VRQALAD-ARAIVLHFQHNVGASTALSQKAE-AVNKESASLVLNDPGRWTTAIDMCESLLELKWV 565

  Fly   337 LSLYCEEYSLVQIYPD-EWIEIDLCSKVMQPCEETIKIWS-----NPSTTTSSVIPLVAALRDSL 395
            :|...||..:.....| :|..:    ..:.|..:|::|.:     :.:...|:::|.:..:...|
Zfish   566 ISSVLEEQKIATNLADHQWRLV----HELVPVLKTVRIAASFLSEDINGPISALMPCLQGVSRLL 626

  Fly   396 RTDVHNFVSSVTICSFARKLLEELE--MKFAHITSDINFL------MATYLDPRYK--------- 443
            ...:.:     ..|...|.::|.:.  |......||.:.|      ::::||||:|
Zfish   627 GQKIAD-----CTCPVVRGVMERIRAGMDKRWSLSDEDALLDCPAVLSSFLDPRFKELRFLSPHA 686

  Fly   444 --------------QAF-----FTEREEQLVANEVLLQLAGVPEDCNGQPPLKIIKVSSTSS--- 486
                          |||     ..|...|.:..|..|...|.|.|......|.|..:.|..|
Zfish   687 RSKLHDKVKELLSVQAFTSNEGLNEDRRQRMEMEEALDEHGDPADFGLDDSLPIPPMGSLDSPES 751

  Fly   487 ------------QKNE-----SKIDSILDSILTTGT----TNTQQPNTSMGSQS----------- 519
                        |.:|     |..:.:.|:.|..|:    ||.::..:|..:.:
Zfish   752 CGSLEEGDSVELQPSELSVAVSSPEQVNDNALEVGSPFKNTNERKRRSSGATMTSPVRGDLQLTS 816

  Fly   520 -------------------------QIKNLLYLYNSEPRIDRNMDPLIWWRS-NIKYISLYGIVR 558
                                     :|...|..|.:||...|::.||.|||| ..::.::..:.|
Zfish   817 RIRMSPLPQSMYDILLGEDPTERMPEIHQQLENYIAEPLCRRSLSPLQWWRSKEHRFPAVARLAR 881

  Fly   559 KFLSAPAASVVSEGLFRKSTHLYFDMQAGLSPESASKMLLMKANFSF 605
            |:||.||.:|.:...|..........:|.|..:..:.:|.:..|..:
Zfish   882 KYLSIPATAVSANRAFAPRESPVTQRRATLGSKHLNHILFLHQNADY 928

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13775	NP_001285694.1	zf-BED	6..48	CDD:280965	15/48 (31%)
CG13775	NP_001285694.1	Dimer_Tnp_hAT	525..603	CDD:283379	22/78 (28%)
si:dkeyp-117b8.4	XP_005165631.1	zf-BED	21..63	CDD:280965
		zf-BED	120..161	CDD:280965	14/41 (34%)
		Dimer_Tnp_hAT	846..925	CDD:283379	22/78 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	1	1.000	-	-		FOG0006504
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920