Protein Alignment SA1 and stag2a

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: NP_001093498.1
• Gene: stag2a / 567168
• ZFINID: ZDB-GENE-030131-3432
• Length: 1246
• Species: Danio rerio
• Alignment Length: 1123
• Identity: 485/1123 - (43%)
• Similarity: 692/1123 - (61%)
• Gaps: 93/1123 - (8%)

  Fly    20 EELHSDALNES---TSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGP 81
            :||.:|...|.   .||.|                     ::|.|       .|..|....:||.
Zfish     5 QELQADFYQEGHSLLSDTD---------------------LEDHE-------GRNGKLAKGKKGK 41

  Fly    82 TERKERVERPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSKNPIASIVDQWIEQYKANRETA 146
            ....|:::.........|||:..|.|      ..||:.|||..|:...|:||.|||.||.:|::|
Zfish    42 KSIGEKLKGSEVRGRVNGHHQENDME------NLSLFEIVRLGKSATQSVVDDWIESYKTDRDSA 100

  Fly   147 LVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRKFKNNFCDF 211
            |:.|:.|||:.|||||.:|.::...:.::.|||:|||||||:||:|||.|:|..|:|||.|.|:|
Zfish   101 LLELINFFIHCSGCKGTVSFEMFRNMQNSEIIRKMTEEFDEDSGDYPLAMAGPAWKKFKTNLCEF 165

  Fly   212 VQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSNNFDN 276
            :.|||:|||||||||:::||.:||||||||||||||||||:||||||:|||||:|||.:|.|.||
Zfish   166 IATLVRQCQYSIIYDEYMMDTLISLLTGLSDSQVRAFRHTSTLAAMKMMTALVNVALNLSINLDN 230

  Fly   277 AAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAIC 341
            ..:|:|.||.||..:||::||:.|:.||.||:||.|||::|:..:||.||:|||||.:.:||.:|
Zfish   231 TQRQYETERNKSIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFIHRYRDVIAEIRVVC 295

  Fly   342 MAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDELKGKLELFTSKFKD 406
            :.|||:||:.|.:.||:||||||:|||::||.|||||:||.:|..||...||..:||||||:|||
Zfish   296 IEEIGMWMKMYSEAFLNDSYLKYVGWTMYDKQGEVRLKCLTALQGLYYSRELNARLELFTSRFKD 360

  Fly   407 RIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLFH 471
            |||:||||||::|:|.|:||:..:|:...|:|..:|||.||.||||:||.||.||.|||..:||.
Zfish   361 RIVSMTLDKEYDVAVQAIKLLTLVLQSSDEVLMAEDCESVYHLVYSAHRPVAVAAGEFLYKKLFS 425

  Fly   472 LTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFID-SNDMVRDWECMTDLLL 535
            .....:|.:.:||: :..|..|:|..|.||:||||||||||||||..| ::::::|||.|..|||
Zfish   426 HHGPEDEGRPRRGR-QCLNANLIRTTVLFFLESELHEHGAYLVDSLWDCASELLKDWESMISLLL 489

  Fly   536 EEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHF 600
            :||.|.||.|.:.||..|||||..:|:|:.....|:||.:.:: .|:|||.|...|::.|:||.|
Zfish   490 DEPFPGEEALSDAQEVALIEIMFCAVRQTCECHPPIGRGTGKR-VLTAKEKKTQLDDRTKITETF 553

  Fly   601 IVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGREVLETC 665
            .|.||.||.||..|.||:.|||..|:||||.:|||.|.|.:|.|||.::..|:..||..:|||.|
Zfish   554 AVALPLLLAKYSMDPEKVTNLLQFPRYFDLEIYTTGRLEKHLDALLRQVRDVVEKHTDTDVLEAC 618

  Fly   666 AKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNITITLKVL 730
            :.|.:.||.:....|.|.::.||.:::..::|:...:|::  |::||| |:|||.|.:..|||.:
Zfish   619 SMTFQALCNDEFTIYNRVDLVRSQMLDEQIDKFHRLLEDF--LLEGEE-PDEDDTYQVLSTLKRI 680

  Fly   731 SILYSSHNLNPWELFKSLFQDVEEAQSKENIDRCLPNEALVYCIEACYFSISWGLQYVENECESV 795
            :..:::|:|..|:||.|.::.:.  ...:|.|  :|.:.:.:.::..::.|.|.|..|..  .|.
Zfish   681 TAFHNAHDLTKWDLFTSNYRLLN--SGLQNGD--MPEQIVAHALQCTHYVILWHLAKVSE--GSA 739

  Fly   796 NVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYK 860
            :..::|. ||..:..|...|........|. ::|.|:..:||.|:|||.::..|..|.:..|.:.
Zfish   740 SKDDMVL-LRRQVRAFCLMCQRYLNSMSTA-VKEQAFTILCDALLIFSYQIVASGREILEPLVFS 802

  Fly   861 SRMDEHLILDNFVQHYVFSLKQDVAQDET--------RIEELHKKRNFLACYCKLVVYNIIPTMR 917
            ........|.||:..:||     |.|||.        :||.||::||.||.:|||:::|::....
Zfish   803 PDASLQSELLNFILDHVF-----VEQDEDGSTDDEAGKIEALHRRRNLLAAFCKLIIFNVVEMKT 862

  Fly   918 AASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSLQEQSEDGI-VSKSSQE 981
            .|.:||.|::.|.|||||||.|:.|||:|:|:..|.||:|||..:|..:  .|:.|. ..:|:..
Zfish   863 GADVFKQYMRYYTDYGDIIKETMSKARQIDKIQCAKTLILSLQQLFNEM--LSDLGCNFDRSTSA 925

  Fly   982 FVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANKEPDDPVRA--PTRLLFLEVLNEFNY 1044
            |..:||||:|||||||.|.:|.||::|.:|:.||.||. |||......  |..|.||::|:||:.
Zfish   926 FCGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAF-KEPSPQGEGGPPLNLAFLDILSEFSS 989

  Fly  1045 KLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHGETD------------------- 1090
            |||:||||.:..:|::.:...|...|.:.|.|||.|||||..|..|
Zfish   990 KLLRQDKKTVHVYLERFMTFQMALQRDDCWLPLISYRNSLQAGADDDTLSVISGMSRSSARSRRG 1054

  Fly  1091 QAPVASKRAYTRKRRDHD 1108
            :.|.|||    ||..|.|
Zfish  1055 KPPAASK----RKLPDED 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	196/359 (55%)
		STAG	190..303	CDD:462502	74/112 (66%)
stag2a	NP_001093498.1	IRR1	89..>382	CDD:227824	179/292 (61%)
		STAG	144..257	CDD:462502	74/112 (66%)