Protein Alignment SA1 and stag1b

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: XP_692120.4
• Gene: stag1b / 563669
• ZFINID: ZDB-GENE-030131-1393
• Length: 1256
• Species: Danio rerio
• Alignment Length: 1130
• Identity: 513/1130 - (45%)
• Similarity: 728/1130 - (64%)
• Gaps: 75/1130 - (6%)

  Fly    22 LHSD--ALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGPTER 84
            ::||  .|.:|::|....|..:.             |...:.||......:|::....::|...:
Zfish     2 INSDFPVLQDSSNDGQGDTISLA-------------ISVSELDDPEVGKGKKKRGRPGKQGAANK 53

  Fly    85 KERVERPRKEPVDKG-------HHERIDSEREITTDENSLYYIVRHSKNPIASIVDQWIEQYKAN 142
            |     .|:.|||||       .|:..:.     ||.::|:.:|:..|:.:.|::|.|||.||.:
Zfish    54 K-----ARRSPVDKGGRRPNGVAHQNGEG-----TDPSTLFEVVKQGKSAMQSVIDDWIESYKQD 108

  Fly   143 RETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRKFKNN 207
            |:.||:.|:.|||:.|||||.:..::...:.:..|||:|||||||:||:|||.|:|.||:||:.|
Zfish   109 RDLALLDLINFFIHCSGCKGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMTGPQWKKFRYN 173

  Fly   208 FCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSN 272
            ||:|:..|::|||||||||:::||.|||||||||||||||||||:||||||||||||:|||.:|.
Zfish   174 FCEFIMVLIRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSI 238

  Fly   273 NFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDI 337
            |.||..:|:||||.|...:||:::|:.|:.||.||:||.|||::|:..:||.:|||||||::.:|
Zfish   239 NQDNTQRQYEAERNKVAGKRANEKLELLLEKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEI 303

  Fly   338 RAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDELKGKLELFTS 402
            ||||:.|||:||:.|...||:||||||:||||||:.|||||:||::|..||...||..||||||:
Zfish   304 RAICIEEIGVWMKLYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQTLYTNRELYPKLELFTN 368

  Fly   403 KFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEFLNV 467
            :||||||:||||||::|:|.|::||..||....:.|:::|||.||.||||:||.||.||.|||:.
Zfish   369 RFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEDALSNEDCENVYHLVYSAHRPVAVAAGEFLHR 433

  Fly   468 RLF--HLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFID-SNDMVRDWEC 529
            :||  | ....||...||.....||..|::.||.||:|||||||.||||||..| |:|:::||:|
Zfish   434 KLFSRH-DPQAEEALAKRRGRNSPNGNLIKMLVLFFLESELHEHAAYLVDSLWDSSHDLLKDWDC 497

  Fly   530 MTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKA 594
            |.:||||:|...||||.::.||.|||:||.:::|:|....||||.:.:: .|:|||.|...|:|.
Zfish   498 MVELLLEDPVQGEEVLGDRHESALIELMVCTIRQAAEAHPPVGRGTGKR-VLTAKEKKTQIDDKN 561

  Fly   595 KLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGR 659
            :||||.||.||.||.|||.|:||:||||.:||||||.:|::.|.|.:|.|||.:|..|:..|...
Zfish   562 RLTEHLIVALPMLLSKYQVDAEKVANLLQIPQYFDLEVYSSGRMEKHLDALLKQIRVVVEKHAEM 626

  Fly   660 EVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNIT 724
            ||||.|:||...||:|......|.:||||.:|:...:|:..::|:   |:|..|..::|||||:.
Zfish   627 EVLEACSKTYSILCSEEYTIMNRVDIARSQLIDELTDKFAHSVED---LLQEGEEADDDDIYNVL 688

  Fly   725 ITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDR-CLPNEALVYCIEACYFSISWGLQYV 788
            .|||.|:..:::|:|..|:|||:.::.:     |..|:: .:|.:..|..::..::||.|.|..:
Zfish   689 STLKKLTAFHNAHDLTKWDLFKNCYRLL-----KMGIEQGSMPEQIAVQALQCSHYSILWQLVKI 748

  Fly   789 ENECESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEH 853
            ...|.|.:  :::| ||..:.:|:..|.:...:..| .::|.|:..:||||:|||.:|.....|.
Zfish   749 TEGCPSKD--DLLA-LRRVVKSFLAVCQQCLSNVNT-PVKEQAFMLLCDLLMIFSHQLVSGGREG 809

  Fly   854 IRGLEYK---SRMDEHLILDNFVQHYVF--------SLKQDVAQDETRIEELHKKRNFLACYCKL 907
            ::.|.:.   |..:|.|   |||..:||        |::.|...:..:||.|||:||.||.:|||
Zfish   810 LQPLVFNPDGSLQNELL---NFVLDHVFIDQDDENQSMEGDEEDEANKIEALHKRRNLLAAFCKL 871

  Fly   908 VVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSL-QEQSE 971
            ::|:|:....||.|||.|:|.|||||||||.||.|.|:::|:..|.||:|||..:|..| |:|..
Zfish   872 IIYDIVDMPAAADIFKQYMKYYNDYGDIIKETLSKTRQMDKIQCAKTLILSLQQLFNELIQDQGP 936

  Fly   972 DGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAAN-KEPDDPVRAPTRLLF 1035
            :  :.::|.....:||||:|||||||.|.||.||:||.:|:.||.||.. ..|..|...|..|.|
Zfish   937 N--LDRTSSHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKVPNPKGPEYPPPNLAF 999

  Fly  1036 LEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHGETDQ-------AP 1093
            ||||.||:.|||:||||.:.|:|:|.:...|...|.:.|.|||.||||||.|..|.       |.
Zfish  1000 LEVLCEFSSKLLRQDKKTVHSYLEKFMTEYMMERREDVWLPLIAYRNSLLTGGDDDRLSVTTGAS 1064

  Fly  1094 VASKRAYTRKRRDHDEEEEEEEDEE 1118
            ..||.:..|.:|....:.:...|||
Zfish  1065 STSKASTVRSKRGRPPQHKRRPDEE 1089

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	196/366 (54%)
		STAG	190..303	CDD:462502	74/112 (66%)
stag1b	XP_692120.4	None