Protein Alignment SA1 and stag2b

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: XP_021328465.1
• Gene: stag2b / 560751
• ZFINID: ZDB-GENE-030131-2785
• Length: 1276
• Species: Danio rerio
• Alignment Length: 1089
• Identity: 494/1089 - (45%)
• Similarity: 700/1089 - (64%)
• Gaps: 57/1089 - (5%)

  Fly    58 DDDEDDFFAPIARKRKTPATRKGPTERKERVERPRKEPVDK--GHHERIDSEREITTDENSLYYI 120
            |.|:.|....|..|.|....:|||.|:.:.:.:    .|.:  |||:....|..:      |:.:
Zfish    26 DFDDPDGRNAIIGKGKAKKGKKGPGEKGKGMGK----GVGRMNGHHQENGMENVM------LFEV 80

  Fly   121 VRHSKNPIASIVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEF 185
            ||..|:.:.|:||.|||.||.:|:.||:.|:.|||..|||||.:|.::...:.::.|||:|||||
Zfish    81 VRLGKSAMQSVVDDWIESYKHDRDVALLDLINFFIQCSGCKGVVSGEMFRNMQNSEIIRKMTEEF 145

  Fly   186 DEESGEYPLIMSGTQWRKFKNNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRH 250
            ||:||:|||.|:|.||:|||::||:|:..||:|||||||||:::||.||||||||||||||||||
Zfish   146 DEDSGDYPLTMTGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRH 210

  Fly   251 TATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIK 315
            |:||||||||||||:|||.:|.|.||..:|:||||.|...:||:|||:.|:.||.||:||.|||:
Zfish   211 TSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANDRLELLLQKRKELQENQDEIE 275

  Fly   316 SMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRC 380
            :|:..:||.||||||||::.:|||||:.|||:||:.|...||:||||||:|||:|||.|||||:|
Zfish   276 NMMNAIFKGVFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKC 340

  Fly   381 LQSLLPLYEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEI 445
            |.:|..||...||..|||||||:||||||:||||||::|:|.|:||:..:|....|:|..:|||.
Zfish   341 LTALQGLYHNRELNAKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLHSSDEVLTAEDCES 405

  Fly   446 VYELVYSSHRGVAQAAAEFLNVRLF-HLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEH 509
            ||.||||:||.||.||.|||..:|| |...:.:....:||: :..|..|::..|.||:|||||||
Zfish   406 VYHLVYSAHRPVAVAAGEFLFKKLFSHRDPEDDSMPKRRGR-QSVNANLIKTTVFFFLESELHEH 469

  Fly   510 GAYLVDSFID-SNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGR 573
            .||||||..| :.::::|||||..|||:||.|.||.|.::||:.||||::.:::|:|....||||
Zfish   470 AAYLVDSMWDCAAELLKDWECMISLLLDEPLPGEEALTDRQETALIEILLCTIRQAAECHPPVGR 534

  Fly   574 ASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQ 638
            .:.:: .|:|||.|...|::.::||.|.:.||:||.||..|:||:.|||.:||:|||.:|||.|.
Zfish   535 GTGKR-VLTAKEKKTQLDDRTRMTELFAIALPALLAKYSVDAEKVTNLLQLPQFFDLEIYTTGRL 598

  Fly   639 EGNLQALLDRINQVMSMHTGREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIE 703
            |.:|.:||.:|.:::..||..:|||.|:||...||.|....:.|.:||||.:::..|:|:...:|
Zfish   599 EKHLDSLLRQIREIVEKHTDTDVLEACSKTYHSLCNEEFTIFNRVDIARSQLLDEQVDKFNKLLE 663

  Fly   704 EWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDRCLPNE 768
            ::   :|..|.|:|||.|.:..|||.:|..|::|:|:.|:||.|.::.:.  ...||.|  :|.:
Zfish   664 DF---LQEGEDPDEDDAYQVLSTLKRISAFYNAHDLSKWDLFTSNYKLLN--TGIENGD--MPEQ 721

  Fly   769 ALVYCIEACYFSISWGLQYVENECESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQ 833
            .:|:.::..::.|.|.|..|...|..   .|.:..||..:..|...|........|. ::|.|:.
Zfish   722 IVVHALQCTHYVILWSLAKVSEGCYK---KEDMLTLRKQMRAFCLMCQRYLTSVNTA-VKEQAFT 782

  Fly   834 SICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVF------SLKQDVAQDET--R 890
            .:||||:|||.::.....|.:..|.|.........|.||:..:||      |...|..||:.  :
Zfish   783 ILCDLLLIFSHQIISGGREALEPLVYTPEASLQSELLNFILDHVFIDQDEDSNSTDGQQDDEAGK 847

  Fly   891 IEELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTL 955
            ||.|||:||.||.||||::||::.....|.|||.|::.|||||||||.|:.|.|:|:|:..|.||
Zfish   848 IEALHKRRNLLAAYCKLIIYNVVEMSTGADIFKQYMRYYNDYGDIIKETMSKTRQIDKIQCAKTL 912

  Fly   956 LLSLITVFKSLQEQSEDG-IVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFA- 1018
            :|||..:|..:  .||.| ...:||..|..:||||:||:||||.|.:|.||::|.:|:.||.||
Zfish   913 ILSLQQLFNEM--LSELGPSFDRSSSAFCGIKELARRFSLTFGLDQLKTREAIAMLHKDGIEFAF 975

  Fly  1019 --ANKEPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYR 1081
              ||.:.|.  ..|..|.||::|:||:.||::|||:.:..:|::.:...|...|.:.|.|||.||
Zfish   976 KEANPQGDG--HPPLNLAFLDILSEFSSKLMRQDKRTVHMYLERFMTFQMALQREDCWLPLISYR 1038

  Fly  1082 NSLLHGETDQ------------APVASKRA--YTRKRRDHDEEEEEEED 1116
            |||..|..|.            :.|.||:|  .|.||:..:||.....:
Zfish  1039 NSLQAGGDDDTMSVVSGISSRGSSVRSKKAKPATAKRKLPEEESSSSSE 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	204/361 (57%)
		STAG	190..303	CDD:462502	77/112 (69%)
stag2b	XP_021328465.1	IRR1	95..>388	CDD:227824	187/292 (64%)
		STAG	150..263	CDD:462502	77/112 (69%)