Protein Alignment SA1 and SA2

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: NP_612109.3
• Gene: SA2 / 38167
• FlyBaseID: FBgn0043865
• Length: 973
• Species: Drosophila melanogaster
• Alignment Length: 1043
• Identity: 295/1043 - (28%)
• Similarity: 489/1043 - (46%)
• Gaps: 124/1043 - (11%)

  Fly    84 RKERVERPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSK--------NPIASIVDQWIEQYK 140
            |:|....|..|||      .:|......|:::.|..|:...:        :.|.|:...|.|.|.
  Fly    25 REECSIAPNDEPV------CVDGTVGDATNKSLLQMILSRKRLSPTNKRNSHIESVAKYWGEFYL 83

  Fly   141 ANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRK-- 203
            .:...|||||:||.:..||...:|.:|...|..::.|:...:..| ..:..||||      ||
  Fly    84 DSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSDILSNSSSHF-SNTHIYPLI------RKPA 141

  Fly   204 --FKNNFCDFVQTLVKQCQYSIIYDQFLMDN-------VISLLTGLSDSQVRAFRHTATLAAMKL 259
              |.|....|:..|:      ::.::|..|:       :.:.:...|:|.:|.||||||:..:|:
  Fly   142 DVFVNQVGSFLNALL------LVANKFRSDSYQLFLVQLTNFVMACSESNIRTFRHTATMIGLKI 200

  Fly   260 MTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEI-KSMLTYMFK 323
            ||.|.|                    :||.|                     ||| .::...||.
  Fly   201 MTILSD--------------------LKSLD---------------------DEIAMTVWMQMFN 224

  Fly   324 SVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRC-LQSLLPL 387
            |:||.|.||.:.|||.:|::|:|.|...||...|..:.|:.....|:|..|:| ::| |.::..|
  Fly   225 SMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGSGDV-IQCSLDNISVL 288

  Fly   388 YEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYS 452
            ..||.|..::...||:|::.:|.:.|.||..::..:|:.:.....:..|||.|..|.::.:|:.:
  Fly   289 CRKDVLFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHVLSAEILTDDVCRVLEQLIMA 353

  Fly   453 SHRGVAQAAAEFLNVRLFHLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSF 517
            ::||:|||||:...:|...|..   ||..:|          |:.|:|.|||.. ||...|||||.
  Fly   354 ANRGLAQAAADLFILRRNGLDG---ETFCQR----------VKHLLQLFIECG-HEQADYLVDSL 404

  Fly   518 IDSNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLS 582
            ||:.::|.||:.|..:|||.|...|  |.:...|:||.|:::.|||:..||:|.||.:
  Fly   405 IDNCELVLDWKSMIAVLLENPKSRE--LSDIHCSSLIAILLAGVKQATAGEIPPGRYT------- 460

  Fly   583 AKELK--AIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQAL 645
             |:||  ..|..:.:.|:.....||.||..|....:.:..||.:|:||..:.|....:.|.|..|
  Fly   461 -KDLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNEL 524

  Fly   646 LDRINQVMSMHT-GREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLI 709
            ::....::...| ...||:...||||.|........|:      .::.|||..||.|....::..
  Fly   525 VEHFELIIFDQTSSTTVLQITVKTLEFLNRMIPIPLTK------QLLNSAVTNYKMAWHRTQDTS 583

  Fly   710 QGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDR--CLPNEALVY 772
            ....|.||.:  .:..||::|::|....||:.|:|.:.|...::....:..:..  .||.||...
  Fly   584 PSRSTHNESN--RLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDDLPPEAFSL 646

  Fly   773 CIEACYFSISWGLQYVENEC-ESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSIC 836
            .::||:..:.|.::.:|... .:|::.|....|.:||:.::...|.|.....|..:....:...|
  Fly   647 YLKACFCCLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTC 711

  Fly   837 DLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDVAQDETRIEELHKKRNFL 901
            ||.::..: |..|....||.:.:....:|..||:.|:..:...|.......||..::|.:.|:.|
  Fly   712 DLFVLHGN-LCGSSNPSIRSVAHVPSGNELDILEGFLMEHFLELSPSDLMLETNSDQLQRIRSIL 775

  Fly   902 ACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVF-KS 965
            ..|.|:|...::|||||:..::||||.:..:||:::.::..|.:.|.::||||:|.:.:.:: |.
  Fly   776 TSYLKVVCLGVVPTMRASKFYEYYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKV 840

  Fly   966 LQEQSEDGIVSKSSQ--EFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANKEPDDPVR 1028
            ..:.:......::.:  ||.:|.|||.|.|.....:.:::||.|.|:||.||.|........|..
  Fly   841 FPDDTRHAAGQRALRPAEFSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELAQKQPTE 905

  Fly  1029 APTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHGETDQAP 1093
            |..:|.||.||..|...||.|||..|::|.:......:|:....:...|..|||:|...:|...|
  Fly   906 ATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDIAHLKEYRNALRPRKTKSYP 970

  Fly  1094 VAS 1096
            .|:
  Fly   971 QAT 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	98/362 (27%)
		STAG	190..303	CDD:462502	29/123 (24%)
SA2	NP_612109.3	IRR1	<115..>329	CDD:227824	71/268 (26%)
		STAG	132..>215	CDD:462502	31/135 (23%)