Protein Alignment SA1 and Stag1

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: NP_001420746.1
• Gene: Stag1 / 315958
• RGDID: 1310744
• Length: 1258
• Species: Rattus norvegicus
• Alignment Length: 1186
• Identity: 520/1186 - (43%)
• Similarity: 736/1186 - (62%)
• Gaps: 135/1186 - (11%)

  Fly    25 DALNESTSDADSPTK------RMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGPTE 83
            |:.||:|:.:|:.::      :..|.|.|.|   :||              ...|.|  ||.|.|
  Rat    11 DSTNETTAHSDAGSELEETEVKGKRKRGRPG---RPP--------------STNKKP--RKSPGE 56

  Fly    84 RKERVE---------RPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSKNPIASIVDQWIEQY 139
             |.|:|         |....|...|..:.:           :|:.:|:..|:.:.|:||.|||.|
  Rat    57 -KSRIEAGIRGVGRGRANGHPQQNGEGDPV-----------TLFEVVKLGKSAMQSVVDDWIESY 109

  Fly   140 KANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRKF 204
            |.:|:.||:.|:.|||..|||:|.:..::...:.:..|||:|||||||:||:|||.|.|.||:||
  Rat   110 KQDRDIALLDLINFFIQCSGCRGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKF 174

  Fly   205 KNNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALL 269
            ::|||:|:..|::|||||||||:::||.|||||||||||||||||||:||||||||||||:|||.
  Rat   175 RSNFCEFIGVLIRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALN 239

  Fly   270 VSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSL 334
            :|.:.||..:|:||||.|...:||::||:.|:.||.||:||.|||::|:..:||.:|||||||::
  Rat   240 LSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAI 304

  Fly   335 PDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDELKGKLEL 399
            .:|||||:.|||:||:.|...||:||||||:||||||:.|||||:||::|..||...||..||||
  Rat   305 AEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLEL 369

  Fly   400 FTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEF 464
            ||::||||||:||||||::|:|.|::||..||....|.|:::|||.||.||||:||.||.||.||
  Rat   370 FTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEF 434

  Fly   465 LNVRLF--HLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFIDSN-DMVRD 526
            |:.:||  | ....||...||.....||..|:|.||.||:|||||||.||||||..:|: ::::|
  Rat   435 LHKKLFSRH-DPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKD 498

  Fly   527 WECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQD 591
            |||||:||||||...||.:.::|||.|||:||.:::|:|....||||.:.:: .|:|||.|...|
  Rat   499 WECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGKR-VLTAKERKTQID 562

  Fly   592 EKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMH 656
            ::.|||||||:|||.||.||.||:||:||||.:||||||.:|:|.|.|.:|.|||.:|..|:..|
  Rat   563 DRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKH 627

  Fly   657 TGREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIY 721
            ...:|||.|:||...||:|......|.:||||.:|:..|:::..::|:   |:|..|..::||||
  Rat   628 VESDVLEACSKTYSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVED---LLQEGEEADDDDIY 689

  Fly   722 NITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDR-CLPNEALVYCIEACYFSISWGL 785
            |:..|||.|:..:::|:|..|:||.:.::.:     |..|:. .:|.:.:|..::..::||.|.|
  Rat   690 NVLSTLKRLTSFHNAHDLTKWDLFGNCYRLL-----KTGIEHGAMPEQIVVQALQCSHYSILWQL 749

  Fly   786 QYVENECESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSE 850
            ..:.:...|   .|.:..||..:.:|:..|.:...:..| .::|.|:..:||||:|||.:|....
  Rat   750 VKITDGSPS---KEDLLVLRKTVKSFLAVCQQCLSNVNT-PVKEQAFMLLCDLLMIFSHQLMTGG 810

  Fly   851 IEHIRGLEYKSRMDEHLILDNFVQHYVF--------SLKQDVAQDETRIEELHKKRNFLACYCKL 907
            .|.::.|.:.........|.:||..:||        |::.|...:..:||.|||:||.||.:.||
  Rat   811 REGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKL 875

  Fly   908 VVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSL-QEQSE 971
            ::|:|:....||.|||:|:|.|||||||||.||.|.|:|:|:..|.||:|||..:|..| |||..
  Rat   876 IIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQEQGP 940

  Fly   972 DGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFA----ANKEPDDPVRAPTR 1032
            :  :.::|.....:||||:|||||||.|.||.||:||.:|:.||.||    ..|..:.|   |..
  Rat   941 N--LDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYP---PPN 1000

  Fly  1033 LLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLL-HGETDQAPV-- 1094
            |.|||||:||:.|||:||||.:.|:|:|.:...|...|.:.|.|||.|||||: .||.|:..|
  Rat  1001 LAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNS 1065

  Fly  1095 ---ASKRAYTR---------KRRDHDEE------------------------------------- 1110
               :||.:..|         ::|..||.
  Rat  1066 GSSSSKTSSVRSKKGRPPLHRKRAEDESLDNTWLNRTDTMIQTPGPLPTPQLTSTVLRENSRPMG 1130

  Fly  1111 EEEEEDEEEH-NDPDY 1125
            |:.:|.|.|| ::||:
  Rat  1131 EQIQEPESEHGSEPDF 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	196/368 (53%)
		STAG	190..303	CDD:462502	74/112 (66%)
Stag1	NP_001420746.1	IRR1	105..>398	CDD:227824	179/292 (61%)
		STAG	160..273	CDD:462502	74/112 (66%)