Protein Alignment SA1 and Stag2

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: NP_001420969.1
• Gene: Stag2 / 313304
• RGDID: 1562042
• Length: 1268
• Species: Rattus norvegicus
• Alignment Length: 1062
• Identity: 492/1062 - (46%)
• Similarity: 699/1062 - (65%)
• Gaps: 59/1062 - (5%)

  Fly    78 RKGPTERKERVERPRKEPVD----KGHHERIDSEREITTDENSLYYIVRHSKNPIASIVDQWIEQ 138
            :|||.|:.:......|.|..    .|||::...|..:      |:.:|:..|:.:.|:||.|||.
  Rat    47 KKGPAEKGKSGNGGGKPPSGPNRMNGHHQQNGVENMM------LFEVVKMGKSAMQSVVDDWIES 105

  Fly   139 YKANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRK 203
            ||.:|:.||:.|:.|||..|||||.::.::...:.::.|||:|||||||:||:|||.|:|.||:|
  Rat   106 YKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKK 170

  Fly   204 FKNNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVAL 268
            ||::||:|:..||:|||||||||:::||.|||||||||||||||||||:||||||||||||:|||
  Rat   171 FKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVAL 235

  Fly   269 LVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDS 333
            .:|.|.||..:|:||||.|...:||::||:.|:.||.||:||.|||::|:..:||.||||||||:
  Rat   236 NLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 300

  Fly   334 LPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDELKGKLE 398
            :.:|||||:.||||||:.|...||:||||||:|||:|||.|||||:||.:|..||...||..|||
  Rat   301 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLE 365

  Fly   399 LFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAE 463
            ||||:||||||:||||||::|:|.|:||:..:|:...|:|..:|||.||.||||:||.||.||.|
  Rat   366 LFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGE 430

  Fly   464 FLNVRLFHLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFID-SNDMVRDW 527
            ||..:||......|:...||...:.||..||:.||.||:|||||||.||||||..| :.::::||
  Rat   431 FLYKKLFSRRDPEEDGIMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDW 495

  Fly   528 ECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDE 592
            |||..||||||...||.|.::|||.|||||:.:::|:|....||||.:.:: .|:|||.|...|:
  Rat   496 ECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKR-VLTAKEKKTQLDD 559

  Fly   593 KAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHT 657
            :.::||.|.|.||.||.||..|:||:.|||.:||||||.:|||.|.|.:|.|||.:|..::..||
  Rat   560 RTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHT 624

  Fly   658 GREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYN 722
            ..:|||.|:||...||.|....:.|.:|:||.:|:...:|:...:|::  |.:||| |:|||.|.
  Rat   625 DTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDF--LQEGEE-PDEDDAYQ 686

  Fly   723 ITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDRCLPNEALVYCIEACYFSISWGLQY 787
            :..|||.::..:::|:|:.|:||...::.::  ...||.|  :|.:.:::.::..::.|.|.|..
  Rat   687 VLSTLKRITAFHNAHDLSKWDLFACNYKLLK--TGIENGD--MPEQIVIHALQCAHYVILWQLAK 747

  Fly   788 VENECESVNVTEVVAELRNNLDTFMGAC-FELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEI 851
            :   .||.:..|.:..|:..:..|...| ..||....||  :|.|:..:||:|:|||.::.....
  Rat   748 I---TESTSTKEDLLRLKKQMRVFCQICQHYLTNVNTTV--KEQAFTILCDILMIFSHQIMSGGR 807

  Fly   852 EHIRGLEY--KSRMDEHLILDNFVQHYVFSLKQD--------VAQDE-TRIEELHKKRNFLACYC 905
            :.:..|.|  .|.:...|:  :|:..:|| ::||        ..:|| ::||.|||:||.||.:|
  Rat   808 DMLEPLVYTPDSSLQSELL--SFILDHVF-IEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFC 869

  Fly   906 KLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSLQEQS 970
            ||:||.::....||.|||.|:|.|||||||||.|:.|.|:|:|:..|.||:|||..:|..:.:
  Rat   870 KLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQ-- 932

  Fly   971 EDGI-VSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANKEPDDPVRA--PTR 1032
            |:|. ..:||..|..:||||:|||||||.|.:|.||::|.:|:.||.||. |||:....:  |..
  Rat   933 ENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAF-KEPNPQGESHPPLN 996

  Fly  1033 LLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHGETDQ------ 1091
            |.||::|:||:.|||:|||:.:..:|:|.:...|...|.:.|.||:.||||||.|..|.
  Rat   997 LAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVIS 1061

  Fly  1092 ------APVASKRA--YTRKRR 1105
                  :.|.||::  .|.||:
  Rat  1062 GMSSRGSTVRSKKSKPSTGKRK 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	200/351 (57%)
		STAG	190..303	CDD:462502	76/112 (68%)
Stag2	NP_001420969.1	IRR1	102..>395	CDD:227824	186/292 (64%)
		STAG	157..270	CDD:462502	76/112 (68%)