Protein Alignment SA1 and Stag3

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: NP_446182.1
• Gene: Stag3 / 114522
• RGDID: 621333
• Length: 1256
• Species: Rattus norvegicus
• Alignment Length: 1087
• Identity: 426/1087 - (39%)
• Similarity: 660/1087 - (60%)
• Gaps: 68/1087 - (6%)

  Fly    58 DDDEDDFFAPIARKRKTPATRKGPTERKERVERPRKEP--VDKGHHERIDSEREI--TTDENSLY 118
            |.|.:|......|||    ..|.|.:.....:.|:|:.  |..|:    |..:.:  |:|   |:
  Rat    63 DSDFEDSLRRNVRKR----AAKRPPKAIPVAKHPKKQSHIVPGGN----DKNKSVPPTSD---LF 116

  Fly   119 YIVRHSKNPIASIVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTE 183
            ..|:.:::...|:||:|:|.||.:.....:.|:.|||.|.|||..::.::...:.::.||:.:||
  Rat   117 DAVKAARSCAQSLVDEWLENYKQDENAGFLELVNFFIRACGCKSTVTPEMFKTMSNSEIIQHLTE 181

  Fly   184 EFDEESGEYPLIMSGTQWRKFKNNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAF 248
            ||:|:||:|||...|..|:||:.:||:||:|||.|||||:::|.|.||::||||.||||||||||
  Rat   182 EFNEDSGDYPLTAPGPSWKKFQGSFCEFVKTLVCQCQYSLLFDGFPMDDLISLLIGLSDSQVRAF 246

  Fly   249 RHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDE 313
            |||:|||||||||:||.|||.:|.:.||..:|:||||.|..::||.:||:||:.||.|.:||.:|
  Rat   247 RHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEE 311

  Fly   314 IKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRL 378
            |:.|:..:|:.||||||||.||:|||:|:.|||.||::|..:||:||||||||||||||..||||
  Rat   312 IEGMMNAIFRGVFVHRYRDILPEIRAVCIEEIGCWMQSYSTSFLNDSYLKYIGWTLHDKHKEVRL 376

  Fly   379 RCLQSLLPLYEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDC 443
            :|:::|..||...||..::||||::||||:|:|.:|:|.||:|.|::|:..|||....:|...||
  Rat   377 KCVKALAGLYSNQELSSRMELFTNRFKDRMVSMVMDRESEVAVEAIRLLTLILKNMEGVLTSADC 441

  Fly   444 EIVYELVYSSHRGVAQAAAEFLNVRLFHLTADMEETKTKRGKVRMPNTPLVRD----LVQFFIES 504
            |.:|.:||.|:|.:|.:|.||:..::||....   .|...|:.|..:....|.    |:.||:||
  Rat   442 EKIYSIVYISNRAMASSAGEFVYWKIFHPECG---AKAVSGRERRRSPQAQRTFIYLLLAFFMES 503

  Fly   505 ELHEHGAYLVDSFID-SNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGE 568
            |.|:|.||||||..| :...::|||.:|.|||::    ::.|.:.||..||||:|||.:|:|.|.
  Rat   504 EHHDHAAYLVDSLWDCAGSYLKDWESLTSLLLQK----DQNLGDMQERMLIEILVSSARQAAEGH 564

  Fly   569 VPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLY 633
            .||||.:.:| :|:|||.|....:|.||.||.|..||.||.|:.||:|.:|.||.:..|||||:|
  Rat   565 PPVGRITGKK-SLTAKERKLQAYDKVKLAEHLIPLLPQLLAKFSADAENVAPLLRLLSYFDLNIY 628

  Fly   634 TTNRQEGNLQALLDRINQVMSMHTGREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKY 698
            .|.|.|.:|:.||.::.:|:..|...||||..|..|..||......::|.:.|||.:::...:::
  Rat   629 CTQRLEKHLELLLQQLQEVVVKHVEPEVLEAAAHALYLLCKPEFTFFSRVDFARSQLVDLLTDRF 693

  Fly   699 KDAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDR 763
            :..:::   |:|.... :||::|::|.|||.||..|::|:|..||:.:...:.:.:|.....:
  Rat   694 QQELDD---LMQSSFL-DEDEVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVDTGEV-- 752

  Fly   764 CLPNEALVYCIEACYFSISWGLQYVENECESVNVTEVVAELRNNLDTFMGACFELTRD-GPTVQI 827
              |::.::..:...||||.|.:.::.   ||.:..:::: |:..:..|...|.....| .|  :|
  Rat   753 --PHQVILPALTLVYFSILWTVTHIS---ESTSQKQLMS-LKKRMVAFCELCQSCLSDVDP--EI 809

  Fly   828 QEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDVA-----QD 887
            ||.|:..:.|||:|||.::.....:.:|.|.:.........|.:|:..:||....::.     :|
  Rat   810 QEQAFVLLSDLLLIFSPQMVVGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGNGQSQED 874

  Fly   888 ETRIEELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFA 952
            ..:||.||::|..||.:|||::|.::....|:.:||:|.|.|.|||||||.||.:||:|::...:
  Rat   875 HVQIELLHQRRRLLAGFCKLLLYGVLELDAASDVFKHYNKFYEDYGDIIKETLTRARQIDRCQCS 939

  Fly   953 MTLLLSLITVFKSL-QEQSEDGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIY 1016
            ..|||||..::..| |||....:....:  |:::::||:||||:||...:.||:.|..:|:.||.
  Rat   940 RILLLSLKQLYTELIQEQGPQDLTELPA--FIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIK 1002

  Fly  1017 FAANK-EPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKII-----PPAMPSSRAEEWQ 1075
            |:.:: .|....|.|..:.|||:|:||:.:|..|||::::|:|:|.:     .|:.|      |.
  Rat  1003 FSLSELPPAGSSREPPNIAFLELLSEFSPRLFHQDKQLLLSYLEKCLQRVSMAPSHP------WG 1061

  Fly  1076 PLILYRNSLLHGE-----TDQAPVASKRAYTRKRRDHDEEEEEEEDE 1117
            |:..|.:||...|     :.|.|..||:......|...|||...:.|
  Rat  1062 PVTTYCHSLHLVENTAEASSQGPPHSKKRCIEVPRRLQEEESSSQGE 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	178/363 (49%)
		STAG	190..303	CDD:462502	70/112 (63%)
Stag3	NP_446182.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..110		13/54 (24%)
		IRR1	102..>426	CDD:227824	171/330 (52%)
		STAG	188..301	CDD:462502	70/112 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1096..1169		5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1230..1256