Protein Alignment SA1 and LOC100486631

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: XP_002937020.2
• Gene: LOC100486631 / 100486631
• XenbaseID: XB-GENE-29078423
• Length: 1158
• Species: Xenopus tropicalis
• Alignment Length: 1126
• Identity: 400/1126 - (35%)
• Similarity: 629/1126 - (55%)
• Gaps: 118/1126 - (10%)

  Fly    20 EELHS---DALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGP 81
            ||.||   ::|:...:..::.|:....:               |.:....|.|||.:..:...
 Frog     8 EEEHSLSQESLHLENNQGENNTQAQKNV---------------DCESLVTPKARKIRRQSENH-- 55

  Fly    82 TERKERVERPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSKNPIASIVDQWIEQYKANRETA 146
             .||...:|.:...:..|     |....:|     |:.:|...|..|.|:|..|:|.|:.:|:.|
 Frog    56 -SRKSSRKRSKDSQITNG-----DRAEAVT-----LFEVVCIGKGAIQSVVSDWVEVYQEDRDAA 109

  Fly   147 LVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDE------------------------ 187
            |:.|:.|:|..|||:|.::.::........|::::||||||
 Frog   110 LLDLLNFYIQCSGCQGVVTAEMFQNQGDKDIMQKLTEEFDEETGLQFKKFMAFPWILTITLADNM 174

  Fly   188 ESGEYPLIMSGTQWRKFKNNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTA 252
            |:|||||..:|..|:||:.|.|:....:|::||||:|||.:|:|.|||||.|||||.:||||||:
 Frog   175 ENGEYPLSKAGNYWKKFRANICELTAVIVQKCQYSVIYDGYLLDTVISLLLGLSDSCIRAFRHTS 239

  Fly   253 TLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSM 317
            ||:|:||.||||.|.|.:..:..|..:.:..|:.:...::.|.|::.:..|::||::..||||||
 Frog   240 TLSAVKLNTALVRVMLNLEISIHNLQRLYNVEQKRFTLKKDSYRMEQIEKKKNELQQKHDEIKSM 304

  Fly   318 LTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQ 382
            :..:||...|.||||.:.|||::|:.|:||||:.||:.:|:|||||||||.|:||:.:|||:.|.
 Frog   305 VEALFKGTIVQRYRDVVADIRSLCIEELGIWMKMYPKVYLNDSYLKYIGWMLYDKVYDVRLKSLL 369

  Fly   383 SLLPLYEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVY 447
            :|..||||| ...|::||:::|||||::||.|::.||||.|:||::.:.:...::|..:||:.:|
 Frog   370 ALQALYEKD-FVDKMDLFSTRFKDRILSMTQDRDHEVSVQAMKLLVRMSQNFEDLLTKEDCDFLY 433

  Fly   448 ELVYSSHRGVAQAAAEFLNVRLFHLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAY 512
            :.||::||.:|.||.|||..|..: .|:.||::..|...|.     .:.|:.|..|::||||..|
 Frog   434 QCVYTTHRPLATAAGEFLYKRYLN-QAEGEESRGTRNNARQ-----FKILLTFICENKLHEHMTY 492

  Fly   513 LVDSFIDSN-DMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASN 576
            ||||..|.| .:::||:|||..||::....|:.|:..||:.||||:::||:|:.....||||.:.
 Frog   493 LVDSLWDYNPKLLKDWQCMTSALLKDTQNGEDALNAIQENLLIEIILASVRQAVEVHPPVGRGTV 557

  Fly   577 RKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGN 641
            || .|||:|.:...:::.|:||||..|||.||.||..|..|:.|||.:.|||...:|::|..:.:
 Frog   558 RK-MLSAREKRVQLEDQIKITEHFARTLPLLLAKYLPDQRKVVNLLQILQYFKFEVYSSNGLDKD 621

  Fly   642 LQALLDRINQVMSMHTGREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWR 706
            |:|||:.:..|...|:..||||.|:|....:..|...:.....:|:..:||..|:.:...:   |
 Frog   622 LKALLNELKHVAMTHSDPEVLEACSKAYMSMGKENVESLVSVVLAKRQLIEQLVDMFSQML---R 683

  Fly   707 NLIQ-GEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKS----LFQDVEEAQSKENIDRCLP 766
            :::| |||..:.:.::.::..||.|:..:::|:.:.|.|::.    |..|:|.        ....
 Frog   684 DMLQEGEEPLSSEGVHQMSCILKKLAAFHNAHDPSEWNLYEKTSQLLLYDLEH--------HWFS 740

  Fly   767 NEALVYCIEACYFSISWG----LQYVENECESVNVTEVVAELRNNLDTFMGAC--FELTRDGPTV 825
            .:.||...:..|:::.|.    ::..|::.|.....|.||       ||...|  :...:||
 Frog   741 VQLLVPAFQCMYYALLWNVVAVMEGTESKVEPAFFKEHVA-------TFWQLCKHYLNHQDG--- 795

  Fly   826 QIQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHL--ILDNFVQHYVFSLKQDVAQDE 888
            .:||.|:.|:||:|::.|         |.|...| ..||..|  .|..||||:||...::..:..
 Frog   796 SVQEQAFMSMCDILLLLS---------HYRDGIY-CYMDSALQSELFAFVQHHVFQSDEEKPKAT 850

  Fly   889 TRIEE--------LHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKARE 945
            .|.|:        |||:|..||.||||:.|||:....|..|:|.|:|.|||:|||||.||.:.|:
 Frog   851 ERSEQDKVMHMEVLHKRRTLLAAYCKLIAYNIVEMAAATEIYKKYMKTYNDFGDIIKETLSRTRQ 915

  Fly   946 INKVNFAMTLLLSLITVFKSLQEQSEDGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAI 1010
            .:::....||:|.|..:|:..:|  ..|..:.||..|.::||:|:|||||||.|.:|.||.:..|
 Frog   916 NDRIESTQTLILCLQQLFQKHRE--AHGSATLSSPSFFNIKEMARRFALTFGMDNVKCRELIVMI 978

  Fly  1011 HRGGIYFAANKEPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQ 1075
            |:.||.||..:...:....|..|.||..::||:.||||.|||::..:|.:.....|......||.
 Frog   979 HKQGIEFAFKESALEENLPPPNLPFLIPISEFSGKLLKADKKILYGYLQRFATEQMLLYDGAEWN 1043

  Fly  1076 PLILYRNSLLHGETDQAPVAS 1096
            ||::|.||||....:::...|
 Frog  1044 PLVIYTNSLLDNVDEESSFTS 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	155/383 (40%)
		STAG	190..303	CDD:462502	52/112 (46%)
LOC100486631	XP_002937020.2	IRR1	98..>417	CDD:227824	141/319 (44%)
		STAG	177..290	CDD:462502	52/112 (46%)