Protein Alignment SA1 and stag3

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: XP_012808812.2
• Gene: stag3 / 100145469
• XenbaseID: XB-GENE-995439
• Length: 1253
• Species: Xenopus tropicalis
• Alignment Length: 1190
• Identity: 435/1190 - (36%)
• Similarity: 671/1190 - (56%)
• Gaps: 116/1190 - (9%)

  Fly     1 MMARRGGKRIRMDDPPPDYE----ELHSDALNESTSDADSPTKRMTRLRARGGVRDKPPIID--- 58
            :|:..|...|. :.|.|.|.    |..:..|..|:..::.|..::.  ..:.|:.:.|.::|
 Frog    11 VMSAHGSSSIE-NSPHPKYSGSSPEGGAPYLTPSSVASEGPVSQLA--SEQRGLDETPTVLDIVT 72

  Fly    59 -------DDEDDFFAPIARKRKTPATRKGPTERKERVERPRKEPVDKGHHERIDSEREITTDENS 116
                   |:..||...::::.:    |..|.| ....:|||              ..|.|.....
 Frog    73 ETDESISDEGSDFEETLSKRPR----RASPGE-TVAAKRPR--------------IAEETVCAKD 118

  Fly   117 LYYIVRHSKNPIASIVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRM 181
            |:..:|..::.:..:||.|::.||.:||.||:.|:.|.:.|.||.|.::.::...:.::.|||:|
 Frog   119 LFEAIRMGRSAMHVLVDDWLDSYKQDREAALLELINFLMLACGCNGVVTLEMLENMQNSDIIRKM 183

  Fly   182 TEEFDEESGEYPLIMSGTQWRKFKNNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVR 246
            |.||:||:.:|||::|...|:||..||.||.:.||.:|||:||||:.|||.:|||||||||||||
 Frog   184 TMEFNEETPDYPLLLSTKPWKKFHANFGDFFKVLVNRCQYNIIYDELLMDALISLLTGLSDSQVR 248

  Fly   247 AFRHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENM 311
            |||||:|.||:|||:.||.||..||::.:...:||..|..||.:.|:.:||::|:.|:..|:.|:
 Frog   249 AFRHTSTFAAVKLMSGLVKVAWDVSHHLNTTKRQFVVEHAKSPETRSPERLEALLAKQRGLQGNL 313

  Fly   312 DEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEV 376
            :|:..|:..:||.||||||.|:..|||||||.|||:||..|.|:||.||.|||:||||:||.|.|
 Frog   314 EEVVDMMNGIFKGVFVHRYCDTSADIRAICMEEIGVWMRTYSQSFLSDSCLKYVGWTLYDKQGAV 378

  Fly   377 RLRCLQSLLPLYEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADK 441
            ||:|:::|..||...|:..|||||||:||:|:|.|.||||.:|:|.|:||:..|.:...::|:.|
 Frog   379 RLQCIRTLHSLYSVPEMAPKLELFTSRFKNRMVFMVLDKEQQVAVEAIKLIGLISQNMEDMLSKK 443

  Fly   442 DCEIVYELVYSSHRGVAQAAAEFLNVR-LFHLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESE 505
            ||:.:|..|:.|.|.|:.||..||..| |.|..|   ||..| |:.|:.|....|.|:.|||:|:
 Frog   444 DCDTIYPFVFVSSRAVSSAAGAFLYQRVLAHTVA---ETSPK-GRNRLGNVSFFRLLMSFFIKSK 504

  Fly   506 LHEHGAYLVDSFID-SNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEV 569
            |.||.||||||..: :...::||.|.|||||.|    ||.||:..||.||||:|:|::|:..|..
 Frog   505 LPEHAAYLVDSLWECAGAPLQDWVCQTDLLLLE----EEGLDDTDESALIEILVASMRQAVEGTS 565

  Fly   570 PVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYT 634
            ||||...|: ..:.|:.||  ::|::||.|.|:.||.||.|:.|||:|:..||.:..:.:|.:|.
 Frog   566 PVGRVPARR-AFALKDRKA--EDKSRLTRHMILALPPLLAKFSADSKKVRTLLKITSFMELEIYC 627

  Fly   635 TNRQEGNLQALLDRINQVMSMHTGREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYK 699
            |:|.|..|..||..:.:::..||..:|||:|::.|..||....|.|.|.:||||.:::....::.
 Frog   628 TDRMEKFLDTLLAEVQEILEKHTEEDVLESCSRALYILCDRKQALYQRADIARSTLMDRLTGRFL 692

  Fly   700 DAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDRC 764
            ..:.|    |..|..|:||.:|||..|:|.:|.|||.|:|:.||||....|.:.:......:
 Frog   693 QQVPE----IMQETEPDEDAVYNIAATMKRISPLYSGHDLSHWELFGPCSQILLKGMDTGEV--- 750

  Fly   765 LPNEALVYCIEACYFSISWGLQYVENECESVN-VTEVVAELRNNLDTFMGACFELTRDGPTVQIQ 828
             |.:.::..:..|:||:.|.|.::.|.....| ::.:..:||...|...|...:|     ...|:
 Frog   751 -PEQIVMAALTCCHFSLLWELFHISNSKGPQNQISPLKQKLRQFCDICQGCLSDL-----NAAIR 809

  Fly   829 EAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDVAQDETRIEE 893
            :.|:..:.|||:||...:|:.:..:::.|.|:..:.....|..|:...||:..:: ..:..|.|.
 Frog   810 KQAFVLLSDLLVIFGSPIAQEQRFYLQPLAYRPSLSLQAELAGFLLDNVFTDPEE-ENEARRTET 873

  Fly   894 LHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLS 958
            ||::||.||.||||::|:.:....|:.||::|||....|||:||.||.|.|.|::.....|:|||
 Frog   874 LHERRNLLAGYCKLILYSSLQLHSASDIFRHYVKFNASYGDLIKETLHKCRSISREETTKTVLLS 938

  Fly   959 LITVFKSLQEQSEDGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFA--ANK 1021
            |...|..|.::. |....:||:.|::::.||:|.||.:|.|..:.|:.:..:|:.||.:.  .||
 Frog   939 LTQAFTELCQEG-DSPPQRSSRPFLEIRGLARRLALLYGPDQRRYRQDIVLLHKEGIKYCLRENK 1002

  Fly  1022 EPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEE---WQPLILYRNS 1083
            ..|   .:|..||||:||:||::|.:|:|||.::.:|::.....:||...::   |.|.:.||.|
 Frog  1003 TSD---WSPQNLLFLDVLSEFSHKTIKEDKKALLRYLEETTERCLPSQPVKDNEIWAPFLAYRKS 1064

  Fly  1084 LL-------HGETDQAP--VASKRAYTR-------KRR--------------------------- 1105
            |.       ..|:|.:|  |.:||:..|       |||
 Frog  1065 LCADEESPPSTESDVSPRRVGTKRSTPRPEVPPQSKRRRGSIGTLDISSLMIEEGKPRLPLMTST 1129

  Fly  1106 DHDEEEEEEEDEEEHNDPDY 1125
            ...|::.....|||.::.||
 Frog  1130 QLKEQKTRTLQEEERSETDY 1149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	165/359 (46%)
		STAG	190..303	CDD:462502	62/112 (55%)
stag3	XP_012808812.2	IRR1	29..>428	CDD:227824	175/419 (42%)
		STAG	192..305	CDD:462502	62/112 (55%)