Protein Alignment CG18304 and mtcl3a

DIOPT Version :10

• Sequence 1: NP_001260170.1
• Gene: CG18304 / 33969
• FlyBaseID: FBgn0031869
• Length: 1901
• Species: Drosophila melanogaster
• Sequence 2: NP_001352779.1
• Gene: mtcl3a / 558933
• ZFINID: ZDB-GENE-100921-84
• Length: 923
• Species: Danio rerio
• Alignment Length: 1062
• Identity: 206/1062 - (19%)
• Similarity: 364/1062 - (34%)
• Gaps: 302/1062 - (28%)

  Fly   916 ARLKRMQLEAEDKLPPRTA-----KRVNDLTPKSHLKKWVEELE------------DEISEMRVM 963
            ||::.......::|||..|     ..:...:|.|.:||.:|||.            ::.|.:|.:
Zfish    36 ARVRSFPSHLLEQLPPGAAADAQTPNLEQPSPHSRMKKKLEELRKRYDFEKDEWRMEKESLLRQV 100

  Fly   964 LSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRG----D 1024
            ....|.:..:.|...|..|||           .:..|:|      ..||..|||.:..:.    :
Zfish   101 AEIQGGENRRMLLELKCVLEE-----------VQSGVKR------EESKRGELELQYTQDRCAWE 148

  Fly  1025 EEAKKLNSKLKDLE--------DKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAK 1081
            .|..:|.|::..||        :.|:..|    ||:|        .|||:.:...|..|....|.
Zfish   149 LERSELKSRITQLEARGCSVVVESVRSPE----LGDT--------LKRERAEQKKLLADTHSAAM 201

  Fly  1082 EKEKLEAKISQLDAELLSAKKSAEKSKSSL----EKEIKDLKTKASKSDSKQVQDLKKQVEEVQA 1142
            :          |...|.::::...|.||.|    |.|.|:.:        .|:.|:::::||:.:
Zfish   202 D----------LRCRLENSERGWMKEKSELLERFESERKEWE--------NQLMDMQRKIEELYS 248

  Fly  1143 SLSAEQKRYE-------DLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIER 1200
            .:.|.:....       .:.......|..|:.......::.||.:.....::|   ..|:|..::
Zfish   249 EVKAHRTGISLRPITDGQIALRLSSCSASTLSSAVTYPSDGQSFEYSEPLTQQ---SNDSIDSQQ 310

  Fly  1201 TDMARKLSEA----------QKRIADLQAKALKTVNGNGAEYERTVLKNKLAEK------EHEYE 1249
            :.::|..||:          ::.:|:.|  |:.|.:..  |...:.||.|:.:|      :....
Zfish   311 SQLSRNASESSELCNNDQIEEQSVAEQQ--AIDTADLE--EILESCLKEKVGKKSWLTGQDVLLN 371

  Fly  1250 RLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQM 1314
            ..||...|.|......:|:|..||..|::..|..:...|.... .|:.|:|:  :.:.:|...|.
Zfish   372 PFRRFQSMEISCGSDKKKNNTSLNAALNEIARASEELCSYQDE-KRKLADIK--RSRSESAFFQR 433

  Fly  1315 KSE-VATVRLRYEQQ-----VKNLSGELTSMQRQ-------CERFKKDRDAFKQMLEVAQKKIGD 1366
            ::| |..|:...|.:     :||:|.:|.|:..|       |
Zfish   434 ETELVERVKDHLEMEDTVLYLKNMSEDLKSIDEQYWMNWECC----------------------- 475

  Fly  1367 LKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERS------- 1424
                        :||.|||..|.:.......|.........|...:|::::.:..:||
Zfish   476 ------------NMHISDDKPKQEDIRQAPPIPIRSTSWYISSPSASELESSVTEQRSGTHPDRK 528

  Fly  1425 -ANEIKISEMQSKLNEFEEERVIGSGSTK--LPGMKTKLELSWQKEREDQQRLLQETSTLARDLR 1486
             .:...:.:.::.|.|.|.:.:..||:|.  :|   |.:.....:...|..|.....|:....::
Zfish   529 YTSPAIVRKFEAMLQENEGKILTDSGNTACIVP---TDINCCQSRWSCDASRFGSNKSSRDIPVK 590

  Fly  1487 QTLFEVE--------RERDKER---LESKRKLDQIKRATEEEMEEGRKKIAE-----------LQ 1529
            :.|...:        .:.|.|.   |:|...|..|......:.|...:|.||           |:
Zfish   591 RCLSNADIADADHSVNQSDAENLNDLKSASHLTNISSLDSPKNERLEQKTAEFNRTLFQAGMGLR 655

  Fly  1530 CDLLELRDVHAKLRTSNEKLRRERERYEKELIKRRMEADGGDRKVGALLQTVDELVKIAPDLKIV 1594
            ||    .|:....||.          ....||......|.....|...|: :.:||:..|:.|
Zfish   656 CD----EDIGMNARTD----------CSPSLISEDTFTDSPLSYVEDNLE-LSDLVQPCPEDK-- 703

  Fly  1595 GSGGSARSSSSSGYDKNLRPEQPNVR--RSRSPSPTLSSSQITSVLARLAEASEELRKFQRVNED 1657
              |....:........:|:.|...::  ::...:|.||..|..|       ||....:.:||.||
Zfish   704 --GRKTETKDRFSMPLSLQQECGEIKPLQTERTTPILSDKQCKS-------ASSPQIQTERVQED 759

  Fly  1658 EQE----RSRMRRSNLRRAASQENDPHGSTSSVASAAGSQRGGGRLSRNSSNNGSLIRKSLSLDH 1718
            ::.    |||:...|..:.::....|                  |...:.||.|::.|...|.:.
Zfish   760 KKSTCSTRSRILDENPWKPSTLAAYP------------------RPVESRSNYGAVERILKSYEE 806

  Fly  1719 SIQRDQNIWRQDDGSVSSMQSIDSELGGLVRDSSLDSRLDSRLSGGSTQSDIPRGPRKKKKGIMG 1783
            ..|:.....::|...:..|                   ||.|....|||
Zfish   807 RSQQPSPGKKEDLMDLLEM-------------------LDKRREPESTQ---------------- 836

  Fly  1784 KLRSLTKSSRNSESEISIQG-SDSDISVASDMRSSKKDLRGRLSGMFKRSGSASRSESMERAGSD 1847
               .||.:..:.|:.:.:|. .:|.::............:.||...:     |||| |:..|.|.
Zfish   837 ---RLTHTPHHKETHVKVQQCKESSVTNKKSFSRPACPAKRRLPSRW-----ASRS-SISSASSP 892

  Fly  1848 QRPVAVTVVGHPDGPQPREPPP 1869
            ..|           |.|..|||
Zfish   893 SPP-----------PTPTPPPP 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18304	NP_001260170.1	SMC_prok_B	<354..1093	CDD:274008	44/205 (21%)
		SMC_prok_B	831..>1544	CDD:274008	141/728 (19%)
		PHA03307	1657..>1901	CDD:223039	41/218 (19%)
mtcl3a	NP_001352779.1	SMC_prok_B	<70..>249	CDD:274008	49/225 (22%)
		DUF4482	201..>254	CDD:464333	14/70 (20%)