Protein Alignment Rat1 and XRN3

DIOPT Version :10

• Sequence 1: NP_609082.1
• Gene: Rat1 / 33964
• FlyBaseID: FBgn0031868
• Length: 908
• Species: Drosophila melanogaster
• Sequence 2: NP_565114.1
• Gene: XRN3 / 843900
• AraportID: AT1G75660
• Length: 1020
• Species: Arabidopsis thaliana
• Alignment Length: 1036
• Identity: 419/1036 - (40%)
• Similarity: 562/1036 - (54%)
• Gaps: 172/1036 - (16%)

  Fly     1 MGVPAFFRWLSRKYPSVIIECNENKQVDADTGRNIYEDPTLPNPNGIEFDNLYLDMNGIIHPCTH 65
            ||||:|:|||:.|||.::.:..|.:.|:.: |..|..|.:.||||.:|:||||||||||||||.|
plant     1 MGVPSFYRWLAEKYPLLVADVIEEEPVEIE-GIKIPVDTSKPNPNNLEYDNLYLDMNGIIHPCFH 64

  Fly    66 PEDKPAPKNEDEMMVAIFECIDRLFGIVRPRKLLYMAIDGVAPRAKMNQQRSRRFRAAKETTEKR 130
            |||:|:|...:|:...:|:.|||||.:|||||||||||||||||||||||||||||:||:.::..
plant    65 PEDRPSPTTFEEVFQCMFDYIDRLFVMVRPRKLLYMAIDGVAPRAKMNQQRSRRFRSAKDASDAA 129

  Fly   131 LEIARIREELLSRGCKLPPEKEKGEHFDSNCITPGTPFMDRLSKCLHYFVHDRQNNNPAWKGIKV 195
            .|..|:|||....|.:||| |...:.||||.|||||.||..||..|.|:||.|.|::..||.|||
plant   130 AEEERLREEFEREGRRLPP-KVDSQVFDSNVITPGTEFMGVLSIALQYYVHLRLNHDVGWKNIKV 193

  Fly   196 ILSDANVPGEGEHKIMDYIRKQRAQPDHDPNTQHVLCGADADLIMLGLATHEPNFTIIRE-EFLP 259
            ||||||||||||||||.|||.||..|..||||:|.|.|.|||||||||||||.:|:|:|| .:.|
plant   194 ILSDANVPGEGEHKIMSYIRLQRNLPGFDPNTRHCLYGLDADLIMLGLATHEVHFSILREVVYTP 258

  Fly   260 NKPRPCDICNGFGHEMDKCVGLGATAPTSANFKPDVPIGAEVKFIFVRLSVLREYLKQTLEMPNL 324
            .:...|.:|...||....|.|........::.|.|.....:..:.|:.:.||||||:..:.:||.
plant   259 GQQERCFLCGQMGHFASNCEGKPKKRAGESDEKGDGNDFVKKPYQFLHIWVLREYLELEMRIPNP 323

  Fly   325 PFEYSFERALDDWVFMCFFVGNDFLPHLPSLEIREGAVDRLVELYKKCVYKTRGYLTDSGDVNLD 389
            |||...||.:||::|:|||||||||||:|:|||||||::.|:.:|||......|||||....||.
plant   324 PFEIDLERIVDDFIFICFFVGNDFLPHMPTLEIREGAINLLMAVYKKEFRSFDGYLTDGCKPNLK 388

  Fly   390 RVQLIMTDLGNAEDQIFKSR----QRREEQFKARDKARKRQERNQDHGSLNQ------SAFG--- 441
            ||:..:..:|:.||:||:.|    ||:.|:.| ||||.|..:|..|.....|      :.|.
plant   389 RVEQFIQAVGSFEDKIFQKRAMQHQRQAERVK-RDKAGKATKRMDDEAPTVQPDLVPVARFSGSR 452

  Fly   442 -ASAVGPNSQQRSVGNYKEEAAALRNRKRTS----------DMANLDDEDEEEN----------- 484
             |||..|:..|.:.|    .:|..:..:|.|          |:.|..:.||.||
plant   453 LASAPTPSPFQSNDG----RSAPHQKVRRLSPGSSVGAAIVDVENSLESDERENKEELKTKLKEL 513

  Fly   485 --------------NDEVRLWEDGFKDRYYESKFDVAPGN--QQFRYAVALQYVRGLCWVLKYYY 533
                          .|:|:|.:.|:::||||.||.|....  ::.|..|.|:|..|||||:.||.
plant   514 IREKSDAFNSDTTEEDKVKLGQPGWRERYYEEKFSVVTPEEMERVRKDVVLKYTEGLCWVMHYYM 578

  Fly   534 QGCASWNWYFPYHYAPFASDFVNIQGLSTMFEKGTKPFNPLEQLMGVFPAASSSHVPEPWAKLMS 598
            :|..||.|::||||||||||..::..:...||.|| ||.|..||:||||||||..:||.:..||:
plant   579 EGVCSWQWFYPYHYAPFASDLKDLGEMDIKFELGT-PFKPFNQLLGVFPAASSHALPERYRTLMT 642

  Fly   599 DPESPIIDFYPEDFKIDLNGKKFAWQGVALLPFVDEKRLFKALVPYYDQLTGEEVKRNKRGDNYL 663
            ||.||||||||.||::|:|||:|:|||:|.|||:||:||.:|:......||.||.:||.|..:.|
plant   643 DPNSPIIDFYPTDFEVDMNGKRFSWQGIAKLPFIDERRLLEAVSEVEFTLTDEEKRRNSRMCDML 707

  Fly   664 YISNQ----------SPHYKKVKKISEKDDESVCKAISFDGMRGTLGKTELNTAISG-----VLK 713
            :|:..          ..|.:::......|.:...|....|||.|.|      |..||     |.:
plant   708 FIATSHRLAELVFSLDNHCRQLSARERVDFKVKIKPKLSDGMNGYL------TPCSGETHPPVFR 766

  Fly   714 SPISGLSDINDNITVTTTFRDPEYDE-------DYIFEAKRLE-NAVDPPQVLPNEQSGNKHRPV 770
            ||:.|:.||..|..:...:|.|:..|       ..||..|.:: ..:.||..|.:|.:|  .||:
plant   767 SPMEGMEDILTNQVICCIYRLPDAHEHITRPPPGVIFPKKTVDIGDLKPPPALWHEDNG--RRPM 829

  Fly   771 IGFNSH--------------------LTRAYVPDSGHRMLNAGIR-------------------- 795
              .|:|                    ::..::.::.||:::..::
plant   830 --HNNHGMHNNHGMHNNQGRQNPPGSVSGRHLGNAAHRLVSNSLQMGTDRYQTPTDVPAPGYGYN 892

  Fly   796 ---------NQQGGGGNGGGGGGYGQGGGYGQGIGGNQ---------GQSYQNNSRNYNYNYNNN 842
                     .|.||.....|..||.|...| |..||.|         .:.||:.||.
plant   893 PPQYVPPIPYQHGGYMAPPGAQGYAQPAPY-QNRGGYQPRGPSGRFPSEPYQSQSRE-------- 948

  Fly   843 YNQH--QGGGYQNNYNNRQQQQYGHNQRFNQDNSNQQQRNFNNYNGPRNNNYQQQGGSRQQ 901
             .||  :||||..|:.|:.|||..|.|      ...:|.|...|||   .::.||||...:
plant   949 -GQHASRGGGYSGNHQNQHQQQQWHGQ------GGSEQNNPRGYNG---QHHHQQGGDHDR 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rat1	NP_609082.1	XRN1	1..735	CDD:227382	365/800 (46%)
XRN3	NP_565114.1	XRN1	1..823	CDD:227382	373/835 (45%)