Protein Alignment TTLL3B and PBY1

DIOPT Version :8

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_009652.2
• Gene: PBY1 / 852391
• SGDID: S000000298
• Length: 753
• Species: Saccharomyces cerevisiae
• Alignment Length: 707
• Identity: 139/708 (20%)
• Similarity: 253/708 (36%)
• Gaps: 185/708 (26%)

  Fly    21 PVSKIQSLIHNLDAELVQLCKQCSVQKPLTSLNNSTSLGSHFSNFGALGGGSGSKTMGGSSSM-- 83
            |.|.....:|.|..|...|.    :..|....|.|   .::.::.|.:||...|...|.:.::
Yeast   112 PASCANIGLHLLSNEPFDLV----LSGPNVGRNTS---AAYITSSGTVGGAMESVITGNTKAIAI 169

  Fly    84 ------GSNNFSPDSIGNLLARVRASTPL-----------PRTVTSSPTAPEAQK-RQMRNVYRT 130
                  |..|.||     ||....:...|           |:|...|...|..:. .....||..
Yeast   170 SWAYFNGLKNVSP-----LLMEKASKRSLDVIKHLVKNWDPKTDLYSINIPLVESLSDDTKVYYA 229

  Fly   131 RVIDAYRNRRIFTVYGNYHTVRRAL-----------MRRGWLEKLPASRHA--KLQSMSEDALLE 182
            .:   :.||.|....|.:..:..:.           :...|..|..|.:.:  .:....:..:|.
Yeast   230 PI---WENRWIPIFNGPHINLENSFAEIEDGNESSSISFNWAPKFGAHKDSIHYMDEYKDRTVLT 291

  Fly   183 HARRGNDYEAVVISKMINHFP--AFFIWQGKGQRDLCAEVRPFRNRVRRSQFLDFSTKVGLVGCA 245
            .|.       |:.|:||:..|  |.|    ||...|..|::    .......|..:..:.:|...
Yeast   292 DAE-------VIESEMISVTPMKATF----KGVNHLLGELK----LTEEENNLSKTNNLIVVSID 341

  Fly   246 EQERWYREDGVCGMSY----------PRFYRLGGNNLEERMAFIEDYQQTQARSLLLYVREHQPA 300
            ..|..|:........|          |.|.. ||...|.::....||:|.....|:
Yeast   342 PMEYIYKPLTHALKKYLPQVEIVSNLPEFDN-GGCEKEMKVFHYGDYEQLDMDKLM--------- 396

  Fly   301 ELISENGTIFSTTLDFALGKVKKMVRHAEHYSLDDARIKPPTPAEIVENQTFMVQSTDVLKSNAK 365
            ||   ....|:.:..:....::|   |...:::                ||:..::.:.:...|
Yeast   397 EL---PNNYFTNSYIYRKALIRK---HFLSHTI----------------QTYTAKNPESILKKA- 438

  Fly   366 FKVSEKVMAEYARLAGLYLDQIESLRPDYRWDGSRNLWILKPGYQSRGIGIVIRSSLDDIL---- 426
            :..|..:..:||......||:...||.:...:.....||:||....:|.||.:..:::|:.
Yeast   439 YLESFTIDLDYAEFLDDALDENWELRQELENESQDKWWIVKPSMSDKGQGIRVFKTIEDLQAIFD 503

  Fly   427 -----------------------QWTSNN-----QNKKYIVQKYIERPLLIY---RTKFDIRQYM 460
                                   ::..||     |.:.:|:|:|:..|||:.   ..||.||.|:
Yeast   504 SFDDEDSEAEESGNDDDADDVNGEFMDNNKVNISQLRHFIIQEYLTNPLLLASMDNRKFHIRCYV 568

  Fly   461 LLTITDTKVSIWTYRDCYLRFSSQEF--------TMDDLRE-SIHLTNNSVQKRYKNKTNRDSRL 516
               :....:.::.|......|:::.|        ::.||:: ..||||..:|.:.|:|   ||.:
Yeast   569 ---VCRGDLQVFVYDRMLALFAAKPFVPLDPYAYSVTDLKDLECHLTNTCLQSKKKDK---DSSV 627

  Fly   517 PKNNMWSLDQFKNYLRIMGAPDGSWSKTYNGFKQNLVA----VVMASLDETEL----LQNAFELY 573
            .:.:  |:::..|             :..:..|:.:.:    |.:|:::...|    |.||||.|
Yeast   628 LEFD--SIEEIPN-------------ERKSNIKEQIHSITNDVFLAAVNVNRLNFQPLPNAFETY 677

  Fly   574 GCDFMLDEHYNPILIEINSTPDLSPSTEITARICPMVLKD----CIRVVVDLPKNPT 626
            |.||::|.:|...|:|||:.||...:.:....:...:..|    |:..:.:..:|.|
Yeast   678 GVDFLIDSNYEVKLLEINAFPDFKQTGKDLKNLIDELFDDTVKYCVTPIFNENRNKT 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:281171	73/357 (20%)
PBY1	NP_009652.2	surE	1..311	CDD:272899	43/225 (19%)
		TTL	389..732	CDD:281171	78/396 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG2157
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000				T1136511
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.615	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1567
TreeFam	0	0.000	Not matched by this tool.
	4	3.840