Protein Alignment Sec61alpha and SPBC19G7.17

DIOPT Version :9

• Sequence 1: NP_001285674.1
• Gene: Sec61alpha / 33905
• FlyBaseID: FBgn0086357
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_595983.2
• Gene: SPBC19G7.17 / 2540769
• PomBaseID: SPBC19G7.17
• Length: 475
• Species: Schizosaccharomyces pombe
• Alignment Length: 476
• Identity: 151/476 - (31%)
• Similarity: 261/476 - (54%)
• Gaps: 14/476 - (2%)

  Fly     2 GIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWIR 66
            |.:|:..|||..|:|||:..|:..::..||:.|.|..:.::.:...||::|...:|:.||....|
pombe     3 GARFINFIKPLSSLLPEVEGPKTHLELVEKLGWMAGCVVVYQILSIIPVYGAEKTDTLDPINNFR 67

  Fly    67 VILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMVITIGQAIV 130
            |:..|:...||..|::||..|..::|:||..|.|.|. :...||.||..|||:...::.:..|:.
pombe    68 VLDGSSASGLMITGLAPIYLSSFLLQILASKKKIAVNFNLIIDRVLFQNAQKVVSALLYLILAVT 132

  Fly   131 YVMTGMYGDPSEIGAGVCLLIIIQLFAAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195
            ||.:|.||..|::|....:::|:|:|..|::.:.|.|:::||:|||||..|.:.::|...|:|..
pombe   133 YVSSGYYGSFSDLGIFRFIMLILQIFLPGIVCIYLCEIIEKGHGLGSGPVLLLGSHILGNIMWDV 197

  Fly   196 FS----PTTVTTGRGTEFEGAVIAL-FHLMATRNDKVRALREAFYRQNLPNLMNLLATVLVFAVV 255
            .|    |  |.....::::||::.. |:|.:.:| |..:||...:|....:.:..|..:.|||..
pombe   198 LSLHRYP--VNESGDSQYQGALVGFAFNLFSFKN-KFSSLRSILFRSEGLSFVQFLVCIAVFATF 259

  Fly   256 IYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFQGNFFINL 320
            :|....|:|:||:|:|.||...::|:||.|||.||:|...:::|:|.|.:..|......:....|
pombe   260 MYTLNIRIDVPIRSSRVRGVRQNFPLKLLYTSVIPLIYFYSILSHLLVFAYALYSLCPNSLITRL 324

  Fly   321 LGVWADVGGGGPARSYPIGGLCYYLSPPESVGHILTDPIHALLYIVFMLGSCAFFSKTWIDVSGS 385
            |..::.:......:...:|||.|:|.||..:...|..|:|.::|.:.::....:||..|::.:..
pombe   325 LVQYSPIDTFAEHKLQLVGGLVYFLYPPLGLSEALLHPVHTVIYTITLICITIYFSLLWMNATAG 389

  Fly   386 SAKDVAKQLKEQHMVMRGHRENSMIHELNRYIPTAAAFGGLCIGALSVMADFLGAIGS--GTGIL 448
            ..:||....||..:|:.|:||.:|:.||.:.||.||......:..|||:|   |...|  |.|:|
pombe   390 GPRDVLLFFKENQLVIAGYREATMLKELEKIIPIAAKLSAFFVSILSVIA---GIFASTFGVGVL 451

  Fly   449 LAVTIIYQYFEIFVKEQSEMG 469
            :|..::|..||:.|...:.:|
pombe   452 IASALVYASFEMIVGANTSLG 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec61alpha	NP_001285674.1	PTZ00219	1..469	CDD:185519	150/474 (32%)
SPBC19G7.17	NP_595983.2	PTZ00219	3..465	CDD:185519	149/467 (32%)
		Plug_translocon	41..73	CDD:287522	8/31 (26%)
		SecY	77..453	CDD:278759	122/381 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10906
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870