Protein Alignment: Sec61alpha and SPBC19G7.17

• Sequence 1: NP_001285674.1
• Gene: Sec61alpha
• FlyBaseID: FBgn0086357
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_595983.2
• Gene: SPBC19G7.17
• PomBaseID: SPBC19G7.17
• Length: 475
• Species: Schizosaccharomyces pombe
• Alignment Length: 476
• Identity: 151/477 (32%)
• Similarity: 261/477 (55%)
• Gaps: 14/477 (3%)

  Fly     2 GIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWIR 66
            |.:|:..|||..|:|||:..|:..::..||:.|.|..:.::.:...||::|...:|:.||....|
pombe     3 GARFINFIKPLSSLLPEVEGPKTHLELVEKLGWMAGCVVVYQILSIIPVYGAEKTDTLDPINNFR 67

  Fly    67 VILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMVITIGQAIV 130
            |:..|:...||..|::||..|..::|:||..|.|.|. :...||.||..|||:...::.:..|:.
pombe    68 VLDGSSASGLMITGLAPIYLSSFLLQILASKKKIAVNFNLIIDRVLFQNAQKVVSALLYLILAVT 132

  Fly   131 YVMTGMYGDPSEIGAGVCLLIIIQLFAAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195
            ||.:|.||..|::|....:::|:|:|..|::.:.|.|:::||:|||||..|.:.::|...|:|..
pombe   133 YVSSGYYGSFSDLGIFRFIMLILQIFLPGIVCIYLCEIIEKGHGLGSGPVLLLGSHILGNIMWDV 197

  Fly   196 FS----PTTVTTGRGTEFEGAVIAL-FHLMATRNDKVRALREAFYRQNLPNLMNLLATVLVFAVV 255
            .|    |  |.....::::||::.. |:|.:.:| |..:||...:|....:.:..|..:.|||..
pombe   198 LSLHRYP--VNESGDSQYQGALVGFAFNLFSFKN-KFSSLRSILFRSEGLSFVQFLVCIAVFATF 259

  Fly   256 IYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFQGNFFINL 320
            :|....|:|:||:|:|.||...::|:||.|||.||:|...:::|:|.|.:..|......:....|
pombe   260 MYTLNIRIDVPIRSSRVRGVRQNFPLKLLYTSVIPLIYFYSILSHLLVFAYALYSLCPNSLITRL 324

  Fly   321 LGVWADVGGGGPARSYPIGGLCYYLSPPESVGHILTDPIHALLYIVFMLGSCAFFSKTWIDVSGS 385
            |..::.:......:...:|||.|:|.||..:...|..|:|.::|.:.::....:||..|::.:..
pombe   325 LVQYSPIDTFAEHKLQLVGGLVYFLYPPLGLSEALLHPVHTVIYTITLICITIYFSLLWMNATAG 389

  Fly   386 SAKDVAKQLKEQHMVMRGHRENSMIHELNRYIPTAAAFGGLCIGALSVMADFLGAIGS--GTGIL 448
            ..:||....||..:|:.|:||.:|:.||.:.||.||......:..|||:|   |...|  |.|:|
pombe   390 GPRDVLLFFKENQLVIAGYREATMLKELEKIIPIAAKLSAFFVSILSVIA---GIFASTFGVGVL 451

  Fly   449 LAVTIIYQYFEIFVKEQSEMG 469
            :|..::|..||:.|...:.:|
pombe   452 IASALVYASFEMIVGANTSLG 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec61alpha	NP_001285674.1	PTZ00219	1..469	CDD:185519	150/475 (32%)
SPBC19G7.17	NP_595983.2	PTZ00219	3..465	CDD:185519	149/468 (32%)
		Plug_translocon	41..73	CDD:287522	9/32 (28%)
		SecY	77..453	CDD:278759	122/382 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR10906
Phylome	1	0.910		0.766	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	3	2.970